About

After the completion of a PhD in 2005, Mark was appointed the senior research scientist of the Queensland Institute of Medical Research arm of the Human Helminth Vaccine Initiative, a multi-national collaborative effort funded by the Bill and Melinda Gates Foundation to develop recombinant vaccines against the human parasitic worms, Necator americanus and Schistosoma mansoni.

In 2009, Mark was granted an NHMRC training fellowship to study how molecules in parasite secretions and on the parasite surface influence the host-parasite relationship with a view to develop anti-worm vaccines and novel therapies for autoimmune disorders. Mid-way through 2011 Mark completed part of this work at the Institute of Infection and Immunology Research at the University of Edinburgh and is now continuing this research at James Cook University.

Interests
Research
  • Mark’s major research focus involves looking at the functions of proteins from human parasites (specifically helminths, or worms) and how these molecules interact with the host immune system.I am particularly interested in understanding these processes in the context of developing vaccines against parasites of third world populations and finding novel therapies for autoimmune disorders such as asthma.
Experience
  • 2011 to present - Research Fellow, James Cook University (Cairns, Qld, Australia)
  • 2009 to 2011 - Research Fellow, University of Edinburgh (Edinburgh, UK)
  • 2006 to 2010 - Research Officer, Queensland institute of Medical Research (Brisbane, Qld, Australia)
  • 2001 to 2005 - PhD Student, Queensland institute of Medical Research (Brisbane, Qld, Australia)
Research Disciplines
Socio-Economic Objectives
Honours
Awards
  • 2011 - Finalist - Australian Museum Eureka Prizes
  • 2010 - Research Australia Griffith University Discovery Award
Fellowships
  • 2009 to 2013 - NHMRC Early Career Training Fellowship
Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles
More

ResearchOnline@JCU stores a total of 19 research outputs authored by Dr Mark Pearson from 2002 onwards.

Current Funding

Current and recent Research Funding is shown by funding source and project.

Sabin Vaccine Institute - Vaccine Development Program

Development of a vaccine for human hookworm disease

Indicative Funding
$45,509 over 2 years
Summary
Hookworms infect 600 million people in developing countries but there is no vaccine available. We are developing recombinant vaccines for human hookworm disease using animal models of infection and human correlates of protective immunity. We are focusing particularly on vaccines which induce antibody responses which target the digestive enzymes the worms use to break down host blood in the parasite's gut. This project is aimed at developing assays to support product development for the Na-APR-1 human hookworm vaccine.
Investigators
Alex Loukas and Mark Pearson, with the help of Darren Pickering (AITHM-Australian Institute of Tropical Health Medicine)
Keywords
Hookworm; Vaccine; neglected tropical disease; Control; Protease; Blood
Supervision

Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor as long as there is also a Level 1 Advisor on the Panel.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current
  • De-allergenising the Hookworm Vaccine Antigen, Na-ASP-2 (PhD, Associate Advisor)
Collaboration

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.

  • 5+ collaborations
  • 4 collaborations
  • 3 collaborations
  • 2 collaborations
  • 1 collaboration
  • Indicates the Tropics (Torrid Zone)

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Email
Phone
Location
  • E4.107, Queensland Tropical Health Alliance (Cairns campus)
Advisory Accreditation
Level 3
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Similar to me

  1. Dr Javier Sotillo-Gallego
    Australian Institute of Tropical Health Medicine
  2. Prof Nick Smith
    Australian Institute of Tropical Health Medicine
  3. Prof Alex Loukas
    Australian Institute of Tropical Health Medicine
  4. Dr Michael Smout
    Australian Institute of Tropical Health Medicine
  5. Mr Darren Pickering
    Australian Institute of Tropical Health Medicine