You are here: Home / Researchers / Program Researchers / Professor Ronald Quinn

Professor Ronald Quinn

Experience

Professor Quinn obtained his PhD from the University of New South Wales (1970), followed by postdoctoral work at Arizona State University, University of Hawaii and the Australian National University. He joined the Roche Research Institute of Marine Pharmacology in Sydney (1974). The period with Roche included one year in Basel (1981). He joined Griffith University (1982) and was appointed Professor (1994). He was elected Fellow of the Australia Academy of Technological Sciences & Engineering (2003) and received the RACI Adrien Albert Award (2004).

Professor Quinn was appointed Director, Eskitis Institute for Cell and Molecular Therapies (2003). The Eskitis Institute was formed via amalgamation of three existing Centres to create critical mass in the University's priority research area of drug discovery. In November 2007, the Eskitis Institute will occupy a second state-of-the-art building on the Brisbane Innovation Park, adjacent to Griffith University's Nathan campus. The two buildings will house 120 Eskitis staff and students.

Profile Page at Griffith University.

Research/Projects

  1. Biodiscovery involving high throughput screening against molecular targets, isolation and structure elucidation of bioactive natural products;
  2. Design and synthesis of receptor ligands and enzyme inhibitors;
  3. Understanding of natural product recognition for biosynthetic enzymes and correlation with therapeutic targets as a rational approach to drug discovery.

 

Key Publications

  1. Yin, S.; Davis, R. A.; Shelper, T.; Sykes, M. L.; Avery, V. M.; Elofsson, M.; Sundin, C.; Quinn, R. J., Pseudoceramines A−D, new antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp. Org. Biomol. Chem2011, 9, 6755-6760.
  2. Rey-Ladino, J.; Ross, A. G.; Cripps, A. W.; McManus, D. P.; Quinn, R., Natural products and the search for novel vaccine adjuvants. Vaccine 2011, 29, 6464-6471.
  3. Holla, H.; Labaied, M.; Pham, N.; Jenkins, I. D.; Stuart, K.; Quinn, R. J., Synthesis of antitrypanosomal 1,2-dioxane derivatives based on a natural product scaffold. Bioorg. Med. Chem. Lett2011, 21, 4793-4797.
  4. Hegde, V.; Campitelli, M.; Quinn, R. J.; Camp, D., Synthesis of novel molecular probes inspired by harringtonolide. Org. Biomol. Chem2011, 9, 4570-4579.
  5. Yang, X.; Feng, Y.; Duffy, S.; Avery, V. M.; Camp, D.; Quinn, R. J.; Davis, R. A., A New Quinoline Epoxide from the Australian Plant Drummondita calidaPlanta Med2011, 77, 1644-1647.
  6. Kellenberger, E.; Hofmann, A.; Quinn, R. J., Similar Interactions of Natural Products with Biosynthetic Enzymes  and Therapeutic Targets could explain why Nature produces such a Large Proportion of Existing Drugs. Nat. Prod. Rep. 2011, 28, 1483-1492.
  7. Xu, M.; Andrews, K. T.; Birrell, G. W.; Tran, T. L.; Camp, D.; Davis, R. A.; Quinn, R. J., Psammaplysin H, a new antimalarial bromotyrosine alkaloid from a marine sponge of the genus PseudoceratinaBioorg. Med. Chem. Lett2011, 21, 846-848.
  8. Le Couteur, D. G.; McLachlan, A. J.; Quinn, R. J.; Simpson, S. J.; de Cabo, R., Aging Biology and Novel Targets for Drug Discovery. J. Gerontol. A Biol. Sci. Med. Sci. 2011, doi: 10.1093/gerona/glr095.
  9. Davis, R. A.; Sykes, M.; Avery, V. M.; Camp, D.; Quinn, R. J., Convolutamines I and J, antitrypanosomal alkaloids from the bryozoan Amathia tortusaBioorg. Med. Chem2011, doi:10.1016/j.bmc.2011.06.006.
  10. Tran, T. D.; Pham, N. B.; Fechner, G.; Quinn, R. J., Chemical investigation of drug-like compounds from the Australian tree, Neolitsea dealbataBioorg. Med. Chem. Lett2010, 20, 5859-5863.

Contact Information

Details found at Griffith University.