About

Dr Aya Taki is an early career Research Fellow at the Molecular Allergy Research Laboratory in the Division of Tropical Health and Medicine, as well as taking part in the Australian Institute of Tropical Health and Medicine, at James Cook University, Townsville. She is currently undertaking multiple projects on fish allergy, funded by the NHMRC project grant, with a strong affiliation to the Centre for Food and Allergy Research (CFAR) based at the Murdoch Childrens Research Institute in Melbourne.

Dr Aya Taki is trained in Vaccinology and Infectious diseases. She has been awarded her Ph.D. at the RMIT University, Melbourne, Australia in Nov 2014, under the supervision of Prof. Peter Smooker. Her doctoral thesis investigated a novel approach to the construction of vaccines. Her research identified that nanoparticles composed of pure protein have great potential as stimulators of immune responses and therefore the new generation of safe and efficacious antigen delivery system. 

Dr Aya Taki’s current research focuses on the characterisation of fish allergens and improvement of diagnostic capacity by the development of the novel in vitro and in vivo IgE-mediated fish allergy tests. Within her current project, she aims to identify a novel, clinically relevant allergens from commonly ingested fish species in 200 fish allergic Australian children by using proteomic and allergenomic approaches, characterise IgE-binding epitopes of fish allergens by NMR spectroscopy, elucidate the structural properties of allergens and understand structure-function relationships in IgE recognition of allergen by using biophysical and immunological techniques.

 

Teaching
  • BC2024: Cell Biology (Level 2; TSV)
  • PC2001: Molecular Basis of Therapeutics 2 (Level 2; TSV)
Interests
Research
  • Allergy
  • Molecular allergology
  • Allergy diagnostics
  • Immunotherapy
  • Vaccinology
  • Nanotechnology
Experience
  • 2016 to present - Post-Doctoral Research Fellow, Australian Institute of Tropical Health and Medicine, College of Public Health, Medical and Veterinary Sciences, James Cook University (Townsville, Australia)
  • 2015 to 2016 - Post-Doctoral Research Fellow, School of Science, RMIT University (Melbourne, Australia)
  • 2004 to 2015 - Teaching Associate, School of Vocational Engineering, Health and Sciences, RMIT University (Melbourne, Australia)
  • 2014 - Research Associate, School of Applied Science, RMIT University (Melbourne, Australia)
  • 2008 to 2014 - PhD in Applied Science (Biotechnology/Applied Biology), School of Applied Science, RMIT University (Melbourne, Australia)
  • 2007 to 2014 - Postgraduate Teaching Associate, School of Science, RMIT University (Melbourne, Australia)
  • 2005 to 2013 - Laboratory Technical Officer, School of Vocational Engineering, Health and Sciences, RMIT University (Melbourne, Australia)
  • 2012 - Clean Tissue Culture Suite Manager, School of Applied Science, RMIT University (Melbourne, Australia)
  • 2007 - Bachelor of Science (Honours) (Biotechnology/Applied Biology), School of Applied Science, RMIT University (Melbourne, Australia)
Research Disciplines
Socio-Economic Objectives
Honours
Awards
  • 2014 - The CASS Foundation Medicine and Science grant
  • 2010 - RMIT the School of Applied Sciences Higher Degrees by Research Scholarship
Memberships
  • 2016 - Australasian Society of Clinical Immunology and Allergy (ASCIA)
  • 2016 - European Associaton of Allergology and Clinical Immunology (EAACI)
  • 2015 - Australasian Society for Immunology (ASI)
  • 2015 - The Victorian Infection and Immunity Network (VIIN)
  • 2015 - International Society for Vaccines (ISV)
  • 2013 - The Molecular Biology Society of Japan (MBSJ)
Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles
Book Chapters
Other research outputs
  • Taki A and Smooker P (2014) The malaria war. Microbiology Australia, 35 (3). pp. 153-155
Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

Australian Nuclear Science and Technology Organisation - Australian Synchrotron Access Program

The structural study of seafood allergen at the Australian Synchrotron

Indicative Funding
$1,473
Summary
This study will perform a comparative analysis of major fish allergens using Australian Synchrotron small-angle X-ray scattering technique. This will determine the structural changes and aggregation behaviour of fish allergens in different physiological conditions simulating the digestive environment. The data generated in this proposed research will shed light on the dynamics of allergen interaction with the immune system that will enable the design and development of modified allergens.
Investigators
Aya Taki in collaboration with Sandip Kamath (College of Public Health, Medical & Vet Sciences and Australian Institute of Tropical Health & Medicine)
Keywords
Allergy; Parvalbumin; Small-angle x-ray scattering; Seafood; Protein Structure; Synchrotron
Supervision

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current
  • Bio Molecular Studies on Allergenic Proteins Causing Fish Allergy in Australian Children for Improved Diagnosis (PhD , Secondary Advisor)
  • Identification and Molecular Characterization of Food Allergens in Aquatic Products from Vietnam (PhD , Secondary Advisor)

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Email
Phone
Location
  • 47.109I, Pharmacy & Medical Research (Townsville campus)
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