
Dr Carla Proietti ~ Research Officer
Australian Institute of Tropical Health & Medicine
- About
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- Research Disciplines
- Socio-Economic Objectives
- Publications
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These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.
- Journal Articles
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- Coghill A, Fang J, Liu Z, Chen C, Jarrett R, Hjalgrim H, Proietti C, Yu K, Hsu W, Lou P, Wang C, Zhao Y, Doolan D and Hildesheim A (2022) Identifying Epstein–Barr virus peptide sequences associated with differential IgG antibody response. International Journal of Infectious Diseases, 114. pp. 65-71
- Ratnatunga C, Tungatt K, Proietti C, Halstrom S, Holt M, Lutzky V, Price P, Doolan D, Bell S, Field M, Kupz A, Thomson R and Miles J (2022) Characterizing and correcting immune dysfunction in non-tuberculous mycobacterial disease. Frontiers in Immunology, 13.
- Sarathkumara Y, Browne D, Kelly A, Pattinson D, Rush C, Warner J, Proietti C and Doolan D (2022) The Effect of Tropical Temperatures on the Quality of RNA Extracted from Stabilized Whole-Blood Samples. International Journal of Molecular Sciences, 23.
- Sarathkumara Y, Browne D, Kelly A, Pattinson D, Rush C, Warner J, Proietti C and Doolan D (2022) The Effect of Tropical Temperatures on the Quality of RNA Extracted from Stabilized Whole-Blood Samples. International Journal of Molecular Sciences, 23 (18).
- Liu Z, Sarathkumara Y, Chan J, Kwong Y, Lam T, Ip D, Chiu B, Xu J, Su Y, Proietti C, Cooper M, Yu K, Bassig B, Liang R, Hu W, Ji B, Coghill A, Pfeiffer R, Hildesheim A, Rothman N, Doolan D and Lan Q (2021) Characterization of the humoral immune response to the EBV proteome in extranodal NK/T-cell lymphoma. Scientific Reports, 11.
- Loiseau C, Traore B, Ongoiba A, Kayentao K, Doumbo S, Doumtabe D, Sousa K, Brady J, Proietti C, Crompton P and Doolan D (2021) Memory CD8 + T cell compartment associated with delayed onset of Plasmodium falciparum infection and better parasite control in sickle?cell trait children. Clinical & Translational Immunology, 10.
- Pearson M, Tedla B, Mekonnen G, Proietti C, Becker L, Nakajima R, Jasinskas A, Doolan D, Amoah A, Knopp S, Rollinson D, Ali S, Kabole F, Hokke C, Adegnika A, Field M, van Dam G, Corstjens P, Mduluza T, Mutapi F, Oeuvray C, Greco B, Chaiyadet S, Laha T, Cai P, McManus D, Bottazzi M, Felgner P, Sotillo J and Loukas A (2021) Immunomics-guided discovery of serum and urine antibodies for diagnosing urogenital schistosomiasis: a biomarker identification study. The Lancet Microbe, 2 (11). pp. e617-e626
- Coghill A, Proietti C, Liu Z, Krause L, Bethony J, Prokunina-Olsson L, Obajemu A, Nkrumah F, Biggar R, Bhatia K, Hildesheim A, Doolan D and Mbulaiteye S (2020) The association between the comprehensive Epstein-Barr Virus serologic profile and endemic Burkitt lymphoma. Cancer Epidemiology, Biomarkers & Prevention, 29 (1). pp. 57-62
- Liu Z, Jarrett R, Hjalgrim H, Proietti C, Chang E, Smedby K, Yu K, Lake A, Troy S, McAulay K, Pfeiffer R, Adami H, Glimelius B, Melbye M, Hildesheim A, Doolan D and Coghill A (2020) Evaluation of the antibody response to the EBV proteome in EBV-associated classical Hodgkin lymphoma. International Journal of Cancer, 147. pp. 608-618
- Loiseau C, Doumbo O, Traore B, Brady J, Proietti C, de Sousa K, Crompton P and Doolan D (2020) A novel population of memory-activated natural killer cells associated with low parasitaemia in Plasmodium falciparum-exposed sickle-cell trait children. Clinical & Translational Immunology, 9 (4).
- Longley R, White M, Takashima E, Brewster J, Morita M, Harbers M, Obadia T, Robinson L, Matsuura F, Liu Z, Li-Wai-Suen C, Tham W, Healer J, Huon C, Chitnis C, Nguitragool W, Monteiro W, Proietti C, Doolan D, Siqueira A, Ding X, Gonzalez I, Kazura J, Lacerda M, Sattabongkot J, Tsuboi T and Mueller I (2020) Development and validation of serological markers for detecting recent Plasmodium vivax infection. Nature Medicine, 26 (5). pp. 741-749
- Proietti C, Krause L, Trieu A, Dodoo D, Gyan B, Koram K, Rogers W, Richie T, Crompton P, Felgner P and Doolan D (2020) Immune signature against Plasmodium falciparum antigens predicts clinical immunity in distinct Malaria endemic communities. Molecular and Cellular Proteomics, 19 (1). pp. 101-113
- More
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ResearchOnline@JCU stores 17+ research outputs authored by Dr Carla Proietti from 2018 onwards.
- Current Funding
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Current and recent Research Funding to JCU is shown by funding source and project.
National Institute of Health - National Institute of Allergy and Infectious Diseases
Development of a T cell based vaccine against malaria from proteome-wide T cell screening
- Indicative Funding
- $2,445,413 over 5 years
- Summary
- This proposal is targeting the development of a malaria vaccine that induced robust and protective T cell responses against the liver stage of the Plasmodium parasite. From the complete P. falciparum pre-erythrocytic (sporozoite/liver) stage proteome, we will identify, characterize, and credential priority antigens discovered by proteome-based T cell screening; and will progress protective antigens through preclinical development to provide a vaccine candidate capable of inducing robust and sustained protective immunity against malaria.
- Investigators
- Denise Doolan, David Pattinson, Carla Proietti, Gavin Painter, Ian Hermans, William R Heath, Matthew McCall and Stephen Hoffman (Australian Institute of Tropical Health & Medicine, Victoria University of Wellington, Malaghan Institute of Medical Research, The University of Melbourne, Radboud University Medical Center and Sanaria)
- Keywords
- Malaria Vaccines; T cell; Antigen Discovery; Preclinical development
National Foundation for Medical Research and Innovation - Portfolio 2 Research Grant
Development of a T cell malaria vaccine
- Indicative Funding
- $290,000 over 2 years
- Summary
- This application seeks to enhance the preclinical package to translate novel Plasmodium falciparum T cell reactive antigens discovered from rational genome-based screening towards clinical testing, to deliver a multi-antigen T-cell based vaccine for malaria ready for clinical trials.
- Investigators
- Denise Doolan, Carla Proietti, David Pattinson and Maggie Veitch (Australian Institute of Tropical Health & Medicine)
- Keywords
- vaccine; Malaria; T cell; vaccine design
- Supervision
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These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.
- Completed
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- Biomarker discovery for EBV-associated cancers and tuberculosis (2023, PhD , External Advisor)
- Collaboration
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The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.- 5+ collaborations
- 4 collaborations
- 3 collaborations
- 2 collaborations
- 1 collaboration
- Indicates the Tropics (Torrid Zone)
My research areas
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