JCU > Research Portfolio > Dr Erik Biros

About

Research Disciplines: Clinical sciences (3202)

Cardiovascular medicine and haematology (3201)
Socio-Economic Objectives: Clinical health (2001)

Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles

Letson H, Morris J, Biros E and Dobson G (2022) ALM induces cellular quiescence in the surgical margin 3 d following liver resection, hemorrhage, and shock. Journal of Surgical Research, 275. pp. 16-28
Letson H, Biros E, Morris J and Dobson G (2022) ALM fluid therapy shifts sympathetic hyperactivity to parasympathetic dominance in the rat model of non-compressible hemorrhagic shock. Shock, 57 (2). pp. 264-273
Rodrigues B, Vangaveti V, Urkude R, Biros E and Malabu U (2022) Prevalence and risk factors of lower limb amputations in patients with diabetic foot ulcers: A systematic review and meta-analysis. Diabetes & Metabolic Syndrome: clinical research & reviews, 16 (2).
Biros E, Vangaveti V and Moran C (2021) Mini-TrpRS is essential for IFNy-induced monocyte-derived giant cell formation. Cytokine, 142. p. 155486
Dobson G, Morris J, Biros E, Davenport L and Letson H (2021) Major surgery leads to a proinflammatory phenotype: differential gene expression following a laparotomy. Annals Of Medicine And Surgery, 71.
Dobson G, Biros E, Letson H and Morris J (2021) Living in a hostile world: inflammation, new drug development, and coronavirus. Frontiers in Immunology, 11.
Kokolevich Z, Biros E, Tirosh O and Reznik J (2021) Distinct ground reaction forces in gait between the paretic and non-paretic leg of stroke patients: a paradigm for innovative physiotherapy intervention. Healthcare, 9 (11).
Krishna S, Li J, Wang Y, Moran C, Trollope A, Mohamed Omer S, Huynh P, Jose R, Biros E, Ma J and Golledge J (2021) Kallistatin limits abdominal aortic aneurysm by attenuating generation of reactive oxygen species and apoptosis. Scientific Reports, 11.
Ly D, Vangaveti V, Urkude R, Biros E and Malabu U (2021) Metabolic and anthropometric influences on nerve conduction parameters in patients with peripheral neuropathy: a retrospective chart analysis. Neurology International, 13 (2). pp. 166-174
Moran C, Biros E, Krishna S, Morton S, Sexton D and Golledge J (2021) Kallikrein-1 blockade inhibits aortic expansion in a mouse model and reduces prostaglandin E2 secretion from human aortic aneurysm explants. Journal of the American Heart Association, 10 (5).
Morris J, Letson H, McEwen P, Biros E, Dlaska C, Hazratwala K, Wilkinson M and Dobson G (2021) Comparison of intra?articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty. Journal of Orthopaedic Surgery and Research, 16.
Morris J, Letson H, McEwen P, Biros E, Dlaska C, Hazratwala K, Wilkinson M and Dobson G (2021) Intra-articular Adenosine, Lidocaine and Magnesium (ALM) solution decreases postoperative joint fibrosis in an experimental knee implant model. Translational Medicine Communications, 6.

More: ResearchOnline@JCU stores 72+ research outputs authored by Dr Erik Biros from 2005 onwards.

Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

United States Department of Defence - DoD Peer Reviewed Orthopaedic Research Program (PRORP) - Applied Research Award

ALM Drug Therapy to reduce inflammation and scar formation after ACL reconstruction surgery: Targeting earlier return to active duty.

Indicative Funding: $1,061,864 over 3 years
Summary: Two complications of anterior cruciate ligament (ACL) reconstruction surgery are cartilage degeneration and scarring within the joint, which can prolong healing, promote pain and restrict knee movement. Our project will evaluate a new therapy known as ALM solution that can be administrered during ACL reconstruction surgery to dampen inflammation, protect cartilage and promote tissue healing within the joint. Our study has the potential to expedite a patient's return to an active duty with fewer complications.
Investigators: Geoffrey Dobson, Peter McEwen, Jodie Morris, Hayley Letson and Erik Biros (College of Medicine & Dentistry)
Keywords: ACL Injury; ACL Reconstruction surgery; Scarring; Osteoarthritis; Inflammation; Therapeutics

Diabetes Australia - General Grant

Extracorporeal Shockwave Therapy for Prevention of Diabetic Foot Ulcer Recurrence: A Pilot Study.

Indicative Funding: $69,500 over 1 year
Summary: Diabetic foot ulcer (DFU) is a common complication of diabetes with a recurrence of up to 40% within one year after initial healing. The common cause for recurrence of DFUs is impaired perfusion of lower extremities due to diabetes. This study aims to determine whether extracorporeal shockwave therapy (ESWT) can prevent the recurrence of previously healed DFUs since it has been shown that low-energy ESWT can improve microcirculation blood flow of ischemic limbs.
Investigators: Usman Malabu, Venkat Vangaveti, Erik Biros, Ramesh Velu, Kunwarjit Sangla and Haleagrahara Nagaraja (College of Medicine & Dentistry)
Keywords: Diabetes Mellitus; Extracorporeal Shockwave Therapy; Diabetic Footlu cers; Prevention

Department of Health and Ageing - Pharmacy Trial Program

Integrated Practice Pharmacists within Aboriginal Community Controlled Health Services

Indicative Funding: $1,040,046 over 2 years (administered by Pharmaceutical Society of Australia)
Summary: Aboriginal and Torres Strait Islander peoples experience a much higher burden of disease due to heart disease, diabetes and other chronic health problems. Many deaths from these illnesses can be prevented if patients are better supported to take their medicines and prescribing quality is improved. This trial will explore if including a practice pharmacist in the primary health care team within Aboriginal community controlled health services (ACCHSs) leads to improvements in the quality of care that Aboriginal and Torres Strait Islander people receive. Our trial will tell us if prescribing by doctors is improved, if patients are more likely to take their medicines, and if indicators of their health are improving over time.
Investigators: Sophie Couzos, Rhondda Jones, Emily Callander, Erik Biros, Deb Smith, Michelle Bellingan, Beverley Glass, Priscilla Page, Donald Whaleboat, Robyn Preston, Nicole Bates, Douglas Boyle, Vicki Slinko, Roderick Wright, Nadia Lusis, Elizabeth Moore and Kathryn Panaretto (College of Medicine & Dentistry, Academy - THM, College of Public Health, Medical & Vet Sciences, The University of Melbourne, Queensland Aboriginal and Islander Health Council, Victorian Aboriginal Community Controlled Health Organisation, Aboriginal Medical Services Alliance Northern Territory and Gidgee Healing Mount Isa Aboriginal Community Controlled Health Services Ltd)
Keywords: Aboriginal Health; integrated health care; continuing quality improvement; Primary Health Care; practice pharmacist; community based participatory research

Supervision

Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current

Physiotherapy for Patients with Persisting COVID-19 Complications: Development of a long Covid Rehabilitation Program (PhD , Secondary Advisor)
Hydrotherapy as a Treatment Regimen for Patients with Intensive Care Unit (ICU) Aquired Weakness (PhD , Secondary Advisor)

Collaboration

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.