JCU > Research Portfolio > Prof Ian Wright

About

I am a clinical academic having trained and worked as a Paediatrician, specialising in Neonatal Medicine in the UK, New Zealand and Australia. More recently I have been also working in medical education.

My research interests have spanned three main areas: microvascular physiology; Opioid exposed infants; Perinatal clinical trials.

My microvacular physiology work commenced in premature neonates but now extends to using the same tools across diferent age groups, disease processes and even species, with work in a number of animal models.

My clinical interests in opioid exposed infants has led me both large scale epimiologicaql studsies of outcomes and development of animal models to understand our treatment and prevention options.

I have been involved in perinatal clinical trials for the past 20 years, leading their uptake in non-capital city centres and resulting in practice changing papers in the highest ranking journals.

I have a developing interest in Health Professional Education research.

Teaching

MD4011: Integrated Pathology and Clinical Medicine Part 1 of 3 (Level 4; TSV)
MD4012: Integrated Pathology and Clinical Medicine Part 2 of 3 (Level 4; TSV)
MD4013: Integrated Pathology and Clinical Medicine Part 3 of 3 (Level 4; TSV)
MD5010: Integrated Clinical Practice Part 1 of 3 (Level 5; TSV)
MD5020: Integrated Clinical Practice Part 2 of 3 (Level 5; TSV)
MD5030: Integrated Clinical Practice Part 3 of 3 (Level 5; TSV)
MD6010: Advanced Clinical Medicine Part 1 of 3 (Level 6; TSV)
MD6020: Advanced Clinical Medicine Part 2 of 3 (Level 6; TSV)
MD6030: Advanced Clinical Medicine Part 3 of 3 (Level 6; TSV)

Research Disciplines

Socio-Economic Objectives

Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles

Eiby Y, Wright I, Stark M and Lingwood B (in press) Red cell infusion but not saline is effective for volume expansion in preterm piglets. Pediatric Research,
Manley B, Buckmaster A, Travadi J, Owen L, Roberts C, Wright I, Davis P and Arnolda G (2022) Trends in the use of non-invasive respiratory support for term infants in tertiary neonatal units in Australia and New Zealand. Archives of Disease in Childhood: fetal and neonatal, 107. pp. 572-576
Oei J, Kapadia V, Rabi Y, Saugstad O, Rook D, Vermeulen M, Boronat N, Thamrin V, Tarnow-Mordi W, Smyth J, Wright I, Lui K, van Goudoever J, Gebski V and Vento M (2022) Neurodevelopmental outcomes of preterm infants after randomisation to initial resuscitation with lower (FiO2 0.6) initial oxygen levels. An individual patient meta-analysis. Archives of Disease in Childhood. Fetal and Neonatal Edition, 107 (4). pp. F386-F392
do Rosario V, Chang C, Spencer J, Alahakone T, Roodenrys S, Francois M, Weston-Green K, Hölzel N, Nichols D, Kent K, Williams D, Wright I and Charlton K (2021) Anthocyanins attenuate vascular and inflammatory responses to a high fat high energy meal challenge in overweight older adults: a cross-over, randomized, double-blind clinical trial. Clinical Nutrition, 40 (3). pp. 879-889
do Rosario V, Fitzgerald Z, Broyd S, Paterson A, Roodenrys S, Thomas S, Bliokas V, Potter J, Walton K, Weston-Green K, Yousefi M, Williams D, Wright I and Charlton K (2021) Food anthocyanins decrease concentrations of TNF-? in older adults with mild cognitive impairment: a randomized, controlled, double blind clinical trial. Nutrition, Metabolism and Cardiovascular Diseases, 31 (3). pp. 950-960
Eiby Y, Lingwood B and Wright I (2021) Plasma Leak From the Circulation Contributes to Poor Outcomes for Preterm Infants: A Working Hypothesis. Frontiers in Neurology, 12.
Huang L, Manley B, Arnolda G, Owen L, Wright I, Foster J, Davis P, Buckmaster A and Dalziel K (2021) Cost-effectiveness of Nasal High Flow versus CPAP for newborn infants in special-care nurseries. Pediatrics, 148 (2).
Hunt R, Liley H, Wagh D, Schembri R, Lee K, Shearman A, Francis-Pester S, DeWaal K, Cheong J, Olischar M, Badawi N, Wong F, Osborn D, Rajadurai V, Dargaville P, Headley B, Wright I and Colditz P (2021) Effect of treatment of clinical seizures vs electrographic seizures in full-term and near-term neonates : a randomized clinical trial. JAMA Network Open, 4 (12).
Kapadia V, Oei J, Finer N, Rich W, Rabi Y, Wright I, Rook D, Vermeulen M, Tarnow-Mordi W, Smyth J, Lui K, Brown S, Saugstad O and Vento M (2021) Outcomes of delivery room resuscitation of bradycardic preterm infants: a retrospective cohort study of randomised trials of high vs low initial oxygen concentration and an individual patient data analysis. Resuscitation, 167. pp. 209-217
Lum J, Bird K, Wilkie J, Millard S, Pallimulla S, Newell K and Wright I (2021) Prenatal methadone exposure impairs adolescent cognition and GABAergic neurodevelopment in a novel rat model of maternal methadone treatment. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 110.
Roach L, Byrne M, Howard S, Johnstone S, Batterham M, Wright I, Okely A, de Groot R, van der Wurff I, Jones A and Meyer B (2021) Effect of omega-3 supplementation on self-regulation in typically developing preschool-aged children: Results of the omega kid pilot study—a randomised, double-blind, placebo-controlled trial. Nutrients, 13 (10).
Roach L, Byrne M, Howard S, Johnstone S, Batterham M, Wright I, Okely A, de Groot R, van der Wurff I, Jones A and Meyer B (2021) The feasibility of the “omega kid” study protocol: A double-blind, randomised, placebo-controlled trial investigating the effect of omega-3 supplementation on self-regulation in preschool-aged children. Nutrients, 13 (1).

More: ResearchOnline@JCU stores 67+ research outputs authored by Prof Ian Wright from 2011 onwards.

Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

Tropical Australian Academic Health Centre Limited - Research Seed Grants

Implementation of Quantified Neonatal Brain MRI at Term-Equivalent Age at Townsville University and Cairns Hospital for Infants at High Risk of Adverse Neurodevelopmental Outcomes

Indicative Funding: $50,000 over 2 years
Summary: Infants born preterm, with low birth weight, or whom have a hypoxic event are at risk for developing adverse neurodevelopmental outcomes. Currently, the timing of MRI is variable at Townsville University and Cairns Hospital?s Neonatal Units, with the infant often being at an age for which anaesthesia is required to undergo an MRI. This project aims to enable neonatal MRI (at term-equivalent age) for infants identified as high risk based, which is safer, less costly, and provides additional information for early personalized treatment plans in comparison to a later MRI (>4 months) - similar to the changes at Royal Brisbane Women?s Hospital.
Investigators: Liza van Eijk, Afroz Keramat, Roslyn Boyd, Jurgen Fripp, Ian Wright, Kerstin Pannek, Prasanna Kumar, Kandasamy Yogavijavan, Mohan Swaminathan, Neil Archer, Margot Bosanquet, Sandhya Menon, Daniel Webb, Carly Luke, Lynda McNamara, Leeann Mick-Ramsamy and Anya Gordon (College of Healthcare Sciences, The University of Queensland, Commonwealth Scientific & Industrial Research Organisation, College of Medicine & Dentistry, Townsville University Hospital and Cairns & Hinterland Hospital & Health Service)
Keywords: Neonatal MRI; Preterm; Quantitative; scoring

Tropical Australian Academic Health Centre Limited - Research Assistance Scheme

Application, evaluation and validation of the Nutrition Education and Screening Tool in Mookai Rosie Bi Bayan; nutrition profiles, their determinants, and associations with birth outcomes.

Indicative Funding: $20,000 over 1 year
Summary: This study takes a participatory action approach to inquiry using mixed traditional/weste rn and quantitative/qualitative methods. To understand the determinants of nutrition-rel ated health outcomes of pregnant Australian Aboriginal women and babies, we must not only be able to empirically measure their dietary intake but seek to understand the motives underlying their dietary decision-making and the cultural factors that influence their dietary decision-making. We aim to determine these factors using a novel digital Nutrition Education and Screening Tool (NEST) and yarning circles.
Investigators: Janelle James, Ian Wright and Karen Yates (College of Medicine & Dentistry and College of Healthcare Sciences)
Keywords: Nutrition; Aboriginal And Torres Strait Islanders; Child health

Australian Health Research Alliance - Women's Health Research Translation Network (WHRTN)

The Far North Queensland My Body, My Baby Project.

Indicative Funding: $15,000 over 2 years
Summary: This project examines nutrition, its determinants and associations with birth outcomes in pregnant First People of Far North Queensland (FNQ) using the Maternal Outcomes and Nutrition Tool (MONT). Successfully piloted in South-East Queensland, the MONT offers a digital data collection tool suitable for use in culturally and linguistically diverse and low-literacy populations. In conducting this research, we aim to establish the nutrition and supplementation patterns exhibited by FNQ?s pregnant First People, identify those at risk of nutrition-related adverse outcomes, inform the development of primary health strategies to mitigate their risk and validate the MONT for use in pregnant First People.
Investigators: Janelle James, Ian Wright and Karen Yates in collaboration with Anthony Perkins and Theresa Simpson (College of Medicine & Dentistry, College of Healthcare Sciences, Griffith University and Mookai-Rosie Bi Bayan)
Keywords: Pregnancy; Nutrition; Birth outcomes; Health Literacy

Far North Queensland Hospital Foundation - Research Grant

The Far North Queensland My Body, My Baby Project.

Indicative Funding: $10,000 over 1 year
Summary: This project examines nutrition, its determinants and associations with birth outcomes in pregnant First People of Far North Queensland (FNQ) using the Maternal Outcomes and Nutrition Tool (MONT). Successfully piloted in South-East Queensland, the MONT offers a digital data collection tool suitable for use in culturally and linguistically diverse and low-literacy populations. In conducting this research, we aim to establish the nutrition and supplementation patterns exhibited by FNQ?s pregnant First People, identify those at risk of nutrition-related adverse outcomes, inform the development of primary health strategies to mitigate their risk and validate the MONT for use in pregnant First People.
Investigators: Janelle James, Ian Wright, Karen Yates and Theresa Simpson in collaboration with Anthony Perkins (College of Medicine & Dentistry, College of Healthcare Sciences, Griffith University and Mookai-Rosie Bi Bayan)
Keywords: Pregnancy; Nutrition; Birth Outcomes; Health Literacy

Far North Queensland Hospital Foundation - Research Grant

Implementation of a Biostatistics, Epidemiology and Research Design support model in the Cairns Clinical Research Unit.

Indicative Funding: $5,000 over 1 year
Summary: This project aims to introduce a biostatistics, epidemiology and research design (BERD) support model into research education and development activities via the CHHHS Clinical Research Unit (CRU). The CRU has historically been central to the conduct of research incubator workshops, monthly drop-in clinics and research cohort support programs. However, researchers at the Cairns Hospital campus don?t yet benefit from an incumbent bio-statistician and epidemiologist. This project aims to provide clinicians access to high-level biostatistics and epidemiology assistance, enhance the capability of the Research Officer through collaborative consultation and assess the efficacy of the BERD model in FNQ clinical research.
Investigators: Janelle James, Ian Wright, Edward Strivens and Susan Richmond (College of Medicine & Dentistry and Cairns & Hinterland Hospital & Health Service)
Keywords: Biostatistics; Research Design; Research Education

Collaboration

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.