Associate Professor John Miles was awarded BSc Hons in 2001 and a PhD in 2008 from the University of Queensland. His work involves understanding basic immune processes which determine the host’s response to infectious disease and chronic conditions. 

He has been awarded a NHMRC Dora Lush Biomedical Postgraduate Scholarship, a NHMRC Overseas Biomedical Fellowship, Welcome Trust VIP Award, WORD Medical Research Fellowship and NHMRC Career Development Fellowships Level 1 and Level 2 (2017-2020). Other awards include the Young Tall Poppy Science Award from the Australian Institute of Policy and Science and Centenary Medal from the Australian Government and her Majesty Queen Elizabeth for Distinguished Service to Medical Research and the Community. John spent 2008-2012 researching immunomonitoring and immune engineering technologies at Cardiff University and was promoted Head of the Human Immunity Laboratory at the QIMR Berghofer Medical Research Institute from 2012-2016. In 2016, John joined the Australian Institute of Tropical Health and Medicine is currently a Principal Research Fellow in Molecular Immunology at the Centre for Biodiscovery and Molecular Development of Therapeutics and the Centre for Biosecurity and Tropical Infectious Diseases. His research has been funded by 12 national and international schemes including Perpetual, NHMRC and ARC.

Experience

• 2016 to present - Consultant, QIMR Berghofer Medical Research Institute (Herston, Australia)
• 2016 to present - Principal Research Fellow & NHMRC Career Development Fellow, Molecular Immunology, Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine (James Cook University, Australia)
• 2008 to present - Research Officer, Cellular Immunology Laboratory, The Queensland Institute of Medical Research (QIMR) (Herston, Australia)
• 2012 to 2016 - Group Leader & NHMRC Career Development Fellow, QIMR Berghofer Medical Research Institute (Herston, Australia)
• 2010 to 2011 - WORD Senior Research Fellow, T Cell Modulation Laboratory, School of Medicine, Department of Infection and Immunity (Cardiff University, Cardiff, United Kingdom)
• 2008 to 2010 - Research Fellow, T Cell Modulation Laboratory, School of Medicine, Department of Infection and Immunity (Cardiff University, Cardiff, United Kingdom)
• 2004 to 2008 - Doctor of Philosophy in Immunology, The University of Queensland (Brisbane, Australia)
• 2002 to 2004 - Research Assistant, Cellular Immunology Laboratory, The Queensland Institute of Medical Research (QIMR) (Herston, Australia)
• 2001 to 2002 - Consultant, The Queensland Department of Primary Industries (DPI); Tick Fever Research Center (TFRC) & Animal Research Institute (ARI) (Brisbane, Australia)
• 2001 - Bachelor of Science (Honours), Microbiology Major, The University of Queensland (Brisbane, Australia)
• 1998 to 2000 - Bachelor of Science, Microbiology and Physiology Majors, The University of Queensland (Brisbane, Australia)

Research Disciplines

• Immunology (1107)

Socio-Economic Objectives

• Clinical Health (9201)

Awards

• National Health and Medical Research Council (NHMRC) Traveling Award for Research Training
• Wellcome Trust VIP Award, ranked 1st in category
• Centenary Medal from the Australian Government and her Majesty Queen Elizabeth II for Distinguished Service to Medical Research and the Community
• Australian Society for Immunology (ASI) Post-doctoral International Travel Award
• The University of Queensland Award for Outstanding Record of Research Performance and Publication; Comprising Certificate and Cash Prize
• Queensland Institute of Medical Research (QIMR) International Travel Award
• Queensland Institute of Medical Research (QIMR) International Postgraduate Travel Award
• Australian Society for Immunology (ASI) Postgraduate International Travel Award
• Health and Medical Research Council (NHMRC) Dora Lush Biomedical Postgraduate Scholarship
• Australian Society for Immunology (ASI) Best Article Prize
• Young Tall Poppy Science Award 2013 from the Australian Institute of Policy and Science.
• Williams Morgan Thomas Bequest Award
• British Society for Immunology (BSI) International Travel Award
• Queensland Cancer Fund (QCF) International Travel Award

Fellowships

• National Health and Medical Research Council (NHMRC) Biomedical Fellowship
• National Health and Medical Research Council (NHMRC) Career Development Fellowship Level 2
• National Health and Medical Research Council (NHMRC) Career Development Fellowship Level 1
• Wales Office of Research and Development (WORD) Medical Research Fellowship

Memberships

• 2017 - Organizing committee, The Australian Tropical Health Conference 2017
• 2015 - Organizing committee, The Brisbane Immunology Group (BIG) Annual Conference 2015
• 2015 - Organizing committee, 46th Australian Society for Immunology Annual meeting 2017
• 2015 - Organizing committee, The 6th Australasian Vaccines & Immunotherapeutics Development Meeting 2016
• 2005 - The Australian Society of Medical Research (ASMR)
• 2003 - The Queensland Institute of Medical Research (QIMR) Information Technology Committee
• 2002 - International Epstein-Barr Virus Association
• 2002 - The Australian Society for Immunology (ASI)
• 2008 to 2012 - The British Society of Immunology (BSI)
• 2001 to 2004 - The Australian Society for Microbiology (ASM)

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles

• Holt M, Miles J, Inder W and Thomson R (in press) Exploring immunomodulation by endocrine changes in Lady Windermere Syndrome. Clinical and Experimental Immunology,
• Law S, Haigh O, Walpole C, Colm K, Miles J, Ghandi M, Radford K and Steptoe R (2019) Simple, rapid and inexpensive typing of common HLA class I alleles for immunological studies. Journal of Immunological Methods, 465. pp. 72-76
• VUCKOVIC S, MINNIE S, SMITH D, GARTLAN K, Watkins T, Markey K, MUKHOPADHYAY P, GUILLEREY C, KUNS R, LOCKE K, PRITCHARD A, Johansson P, VARELIAS A, ZHANG P, HUNTINGTON N, WADDELL N, CHESI M, Miles J, SMYTH M and HILL G (2019) Bone marrow transplantation generates T cell–dependent control of myeloma in mice. Journal of Clinical Investigation, 129 (1). pp. 106-121
• Wangchuk P, Shepherd C, Constantinoiu C, Ryan R, Kouremenos K, Becker L, Jones L, Buitrago G, Giacomin P, Wilson D, Daly N, Mcconville M, Miles J and Loukas A (2019) Hookworm-derived metabolites suppress pathology in a mouse model of colitis and inhibit secretion of key inflammatory cytokines in primary human leukocytes. Infection and Immunity, 87 (4).
• Fernandez-Rojo M, Deplazes E, Pineda S, Brust A, Marth T, Wilhelm P, Martel N, Ramm G, Mancera R, Alewood P, Woods G, Belov K, Miles J, King G, Ikonomopoulou M and (2018) Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells. Cell Death Discovery, 4. pp. 1-11
• Goldenberg J, Cipriani V, Jackson T, Arbuckle K, Debono J, Dashevsky D, Panagides N, Ikonomopoulou M, Koludarov I, Li B, Santana R, Nouwens A, Jones A, Hay C, Dunstan N, Allen L, Bush B, Miles J, Ge L, Kwok H and Fry B (2018) Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis). Comparative Biochemistry and Physiology - Part C, 205. pp. 53-61
• Hayward T, Zhu G, Warrington N, Wong Y, Ryan R, Murray A, Haigh O, Martin N, Miles J and Evans D (in press) Antibody response to common human viruses is shaped by genetic factors. The Journal of Allergy and Clinical Immunology,
• Ikonomopoulou M, Fernandez-Rojo M, Pineda S, Cabezas-Sainz P, Winnen B, Morales R, Brust A, Sánchez L, Alewood P, Ramm G, Miles J and King G (2018) Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation. Scientific Reports, 8.
• Jimenez R, Ikonomopoulou M, Lopez J and Miles J (2018) Immune drug discovery from venoms. Toxicon, 141. pp. 18-24
• Lepletier A, Lutzky V, Mittal D, Stannard K, Watkins T, Ratnatunga C, Smith C, McGuire H, Kemp R, Mukhopadhyay P, Waddell N, Smyth M, Dougall W and Miles J (in press) The immune checkpoint CD96 defines a distinct lymphocyte phenotype and is highly expressed on tumor-infiltrating T cells. Immunology and Cell Biology,
• Lutzky V, Ratnatunga C, Smith D, Kupz A, Doolan D, Reid D, Thomson R, Bell S and Miles J (2018) Anomalies in T cell function are associated with individuals at risk of Mycobacterium abscessus complex infection. Frontiers in Immunology, 9.
• McGuire H, Watkins T, Field M, Taylor S, Yasuyama N, Farmer A, Miles J and Fazekas de St. Groth B (2018) TCR deep sequencing of transgenic RAG-1-deficient mice reveals endogenous TCR recombination: a cause for caution. Immunology and Cell Biology, 96 (6). pp. 642-645

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ResearchOnline@JCU stores 102+ research outputs authored by A/Prof John Miles from 2003 onwards.

Current and recent Research Funding to JCU is shown by funding source and project.

Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current

• Identification of viral versus bacterial triggers in immune cells from AECOPD patients (PhD , Primary Advisor/AM/Adv)
• High-Throughput and High-Definition Breakdown of Human T Cell Repertoires in Health and Disease (PhD , Primary Advisor/AM/Adv)
• First aid of tropical jellyfish stings (PhD , Advisor Mentor)
• C. Fleckeri Mode of Action Investigation (Masters , Secondary Advisor/AM)

Completed

• Deconstructing the immunopathogenesis of lung infections (2019, PhD , Primary Advisor/AM/Adv)

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.