Dr Jordan is an NHMRC/MSRA (Betty Cuthbert) research fellow having completed a PhD in Immunogenetics at James Cook University, Townsville under the supervision of Professor Alan Baxter. She has extensive years of experience in Immunogenetics dissecting the genetics of Type 1 Diabetes, SLE, experimental autoimmune gastritis and Multiple Sclerosis. She has been a member of the Australasian Society for Immunology (ASI) since 1998 and the Australsian Genomic Technologies Association (AGTA, formally AMATA) since 2010. She is a Grant Reviewer for National Health and Medical Research Council (NHMRC), Diabetes Australia Research Trust (DART),  Rebecca L. Cooper Foundation  and Multiple Sclerosis Research Australia (MSRA) and is a member of the Queensland branch of the ASI committee. She is a reviewer for Clinical and Experimental Immunology Journal and has been an abstract reviewer for the International Congress of the Immunology of Diabetes Society and Brisbane Immunology Group meeting. Her work is funded by the NHMRC, MSRA, the Rebecca L. Cooper Foundation and the Lions Club. Dr Jordan became Honours' co-ordinator (Molecular and Cell Biology) in 2013 and Director of Research (Molecular and Cell Biology) in 2015, both roles of which are still current.  She also serves on the Animal Ethics Commitee and is an ethics monitor for the Human Ethics Committee.


Her current research focus is the identification of multiple sclerosis genes in man using gene expression arrays on sorted white blood cells. She has also utilised genetic linkage analyses and congenic mouse strains for gene expression microarray profiling to identify disease-associated candidate genes in other autoimmune dideases, such as SLE, T1D and autoimmune gastritis.  She has identified genes controlling the immunoregulatory subset, NKT cells, whose candidacy she subsequently confirmed  by producing transgenic and knock out strains. In addition, she is proficient in qPCR, sequencing and microsatellite/SNP typing. She has extensive experience working with DNA, RNA and proteins, cell preparations for flow cytometry, immunofluorescence and immunohistochemistry.screening of numerical aberrations.

In addition, Dr Jordan has 11.5 years experience as a Medical Scientist in Cytogentics becoming expert in identifying chromosome anomalies in human blood, bone-marrow, amniotic fluid and CVS samples. She established/cryopreserved and deposited human EBV-transformed cell lines in Coriell Cell Repositories; extracted DNA for population studies of peoples of Sub-Saharan origin; prepared centomeric probes and chromosome paints. She was instrumental in establishing the FISH division within the Cytogenetics Unit, S.A.I.M.R. which facilitated further research of patient samples to better define translocations and the interphase analysis of numerical anomalies.

  • BC3102: Molecular Basis of Disease (Level 3; TSV)
  • BC5102: Advanced Molecular Basis of Disease (Level 5; TSV)
  • PC2204: Pharmacology and Pharmacogenomics for Pharmacists (Level 2; TSV)
  • PC3301: Integrated Therapeutics 2 (Level 3; TSV)
  • Multiple Sclerosis (MS)
  • Type 1 Diabetes (T1D)
  • Systemic Lupus Erythematosis (SLE)
  • Autoimmunity
  • Autoimmune Gastritis
  • Immunology
  • Genomics
  • Immunogenetics
  • Genetics of Immune Regulation
  • 2015 to present - Director of Research (Molecular and Cell Biology), James Cook University (Townsville, Australia)
  • 2014 to present - Human Ethic Monitor, James Cook University (Townsville, Australia)
  • 2014 to present - Senior Research Fellow, CGC, James Cook University (Townsville, Australia)
  • 2013 to present - Honours co-ordinator (Molecular and Cell Biology), James Cook University (Townsville, Australia)
  • 2015 to 2019 - AEC Member, James Cook University (Townsville, Australia)
  • 2003 to 2013 - Research Fellow, CGC, James Cook University (Townsville, Australia)
  • 1998 to 2003 - Research Assistant, Centenary Institute for Molecular Biology and Cancer Research (Sydney, Australia)
  • 1997 to 1998 - Hospital Scientist, New Childrens's Hospital (Sydney Australia)
  • 1997 - Cytogeneticist, Sydney Genetics (Sydney, Australia)
  • 1986 to 1997 - Medical Scientist, South African Institute for Medical Research (Johannesburg, South Africa)
Research Disciplines
  • 2020 to 2021 - Single Cell Access grant from CTBMT
  • 2019 to 2020 - ASI Travel Award
  • 2019 to 2020 - TAAHC grant
  • 2016 to 2020 - MSRA (Multiple Sclerosis Research Australia) Project grant
  • 2019 - Travel award to attend Brisbane Immunology Group Meeting, Sunshine Coast, Brisbane
  • 2016 - International travel award from ICG (International congress genetics) to attend ICG, 2016, Dalian, People's Republic of China
  • 2014 to 2016 - AI on NHMRC grant #1061580 (Novel posttranscriptional pathways that control Tfh cell numbers. CIA Prof Carola Vinuesa CIB Dr Julia Ellyard, ANU $626 226.00
  • 2014 to 2015 - Rising Stars ECR Leadership Program grant
  • 2014 - Rebecca L. Cooper Research Foundation Grant
  • 2013 - ASI Travel grant to attend ICI (International congress of immunology), Milan, Italy 2013
  • 2013 - Wellcome Trust international travel award to attend The Genomics of Common Diseases conference, Oxford, UK.
  • 2013 - Equipment grant
  • 2013 - Competitive Research Incentive grant (CRIG)
  • 2013 - JCU MHMS Faculty travel grant to attend “Science Pathways” Conference, 17-18 October 2013, AMREP Education Centre, Melbourne, VIC.
  • 2012 to 2013 - FAIG (Medicine, Health & Molecular Sciences Grants Scheme 2012 (Early Career Researchers)
  • 2010 - AMATA Travel award
  • 2009 - FIMSA/ASI Travel award
  • 2007 - Logan Foundation Travel Scholarship
  • 2007 - ASI-BIG Medal for Best Poster Presentation
  • 2006 - Science Communicators Award for Best Oral Presentation, ThymOz
  • 2006 - ASI-BIG Medal for Best Poster Presentation
  • 2006 - Townsville festival of Life Sciences Poster prize
  • 2006 - ASI International Travel Award
  • 2006 - JDRF Travel award
  • 2005 - ASI National Travel award
  • 2021 - 10X Genomics & Millenium Science "Start Single Cell" Fellowship Program
  • 2013 to 2016 - NHMRC/MSRA Betty Cuthbert Fellowship
  • 2014 to 2020 - Human Ethics Research monitor
  • 2012 to 2020 - ASI Queensland commitee member
  • 2010 to 2020 - Member of Australian Microarray Associated Technologies Association (AMATA) now AGTA (Australian Genome Technologies association)
  • 1998 to 2020 - Member of the Australasian Society for Immunology
  • 2015 to 2019 - Animal Ethics Committee member
  • 1986 to 1997 - Member of the South African Society for Human Genetics
  • 2011 - Editorial responsibilities with Clinical and Experimental Immunology Journal
  • 2015 to 2020 - Grant reviewer for HDRES student research grants
  • 2015 to 2020 - Judge of “3MT Thesis contest”, JCU
  • 2014 to 2020 - Grant reviewer for National Health & Medical Research Council (NHMRC)
  • 2013 to 2020 - Grant reviewer for Multiple Sclerosis Research Australia (MSRA)
  • 2019 - Session chair for BIG Plenary Lecture, BIG conference, Sunshine Coast, QLD
  • 2019 - Scientific committee member and organiser of Brisbane Immunology Group meeting, Sunshine Coast, QLD
  • 2018 - Invited speaker, International Congress of Neuroimmunology, Brisbane
  • 2014 to 2018 - Grant reviewer for Rebecca L Cooper foundation
  • 2017 - Judge of “Science Communication Award”, ASI, Brisbane
  • 2017 - Session chair for Autoimmunity Session, ASI conference, Brisbane
  • 2015 to 2017 - Scientific committee member and Organiser of Australain Society for Immunology (ASI) meeting, Brisbane, QLD, 2017
  • 2014 to 2017 - Organizer of "Day of Immunology" events, Townsville
  • 2016 - Invitation to deliver an oral presentation at ICG, Dalian, People's Republic of China
  • 2012 to 2016 - Grant reviewer for Diabetes Australia Research Trust ( DART)
  • 2015 - Judge for oral presentations: Townsville Health Symposium, Townsville Hospital
  • 2014 - Selected as NHMRC project grant panel observer
  • 2014 - Session chair for ECR session BIG conference, Gold Coast
  • 2012 to 2014 - Faculty representitive of the Gender Equity Working Group (GEWG)
  • 2013 - Invited speaker MS Angels event, Brisbane, November, 2013
  • 2013 - Invited speaker MS Angels event, Brisbane, April, 2013
  • 2009 - Invited speaker BIG (Brisbane Immunology Group) meeting, Brisbane, QLD
  • 1986 to 1998 - Registration with the Medical Scientist Association

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles
Book Chapters

ResearchOnline@JCU stores 34+ research outputs authored by Dr Margaret Jordan from 1995 onwards.

Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

Tropical Australian Academic Health Centre Limited - Contract Research

Genomics of lung cancer in Indigenous people of North Queensland

Indicative Funding
$50,000 over 1 year
Cancer genomic profiling is a major determinant of chemotherapy selection for non-small cell lung cancer and is widely used internationally. Indigenous genomes carry ~10X more uncharacterised DNA sequence variation than people of European heritage. THHS is currently trialling the use of whole exome sequencing, instead of the existing 4 gene panel, to base choice of targeted therapies in lung cancer. This creates an opportunity to study whether the cancer-associated variation currently being used to select therapies is adequate, and if not, these data will form the foundation for an NHMRC funding application to identify improved markers.
Alan Baxter, Sabe Sabesan, Martin Nakata, Margaret Jordan, Justin Lee and Letitia Smith in collaboration with Matt Brown and Trevor Prior (College of Public Health, Medical & Vet Sciences, Townsville Hospital and Health Services, Indigenous Education & Research Centre and Queensland University of Technology)
Cancer; Non-small cell lung cancer; Genomics; Whole exome sequencing; Indigenous health care; Closing The Gap

Multiple Sclerosis Research Australia - Project Grant

An immune transcriptional regulatory network approach to Multiple Sclerosis

Indicative Funding
$240,000 over 4 years
Multiple Sclerosis (MS) is an autoimmune disease resulting from a complex interaction between genetic and environmental factors. In an attempt to understand the integration of both sets of risk factors, we have compared mRNA transcripts between relapsing/remitting (RR) MS patients and healthy controls in 5 leukocyte subsets: CD4 and CD8 T cells, B cells, NK cells and monocytes. A gene co-expression network was generated based on correlation of expression levels across >700 gene expression microarrays, and a major co-ordinately regulated sub-network (module) of mRNA transcripts that is differentially expressed in the monocytes of RR-MS patients was identified. This project validates, characterizes and attempts to manipulate this transcriptional module in human cells ex-vivo and in the experimental autoimmune encephalomyelitis (EAE) model of central nervous system (CNS) autoimmunity. These results should provide greater explanatory power than the analyses of individual risk factors separately and may provide a multi-faceted target for intervention.
Alan Baxter, Margaret Jordan, Helmut Butzkueven and Louise Laverick in collaboration with Letitia Smith (College of Public Health, Medical & Vet Sciences and The University of Melbourne)
Autoimmunity; Cellular Immunology; Immunogenetics; Multiple Sclerosis; mouse models; humans

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These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

  • Causes of Multiple Sclerosis: A Functional Genomics Approach. (PhD , Primary Advisor)

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.

  • 5+ collaborations
  • 4 collaborations
  • 3 collaborations
  • 2 collaborations
  • 1 collaboration
  • Indicates the Tropics (Torrid Zone)

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