• MD4011: Integrated Pathology and Clinical Medicine Part 1 of 3 (Level 4; TSV)
  • MD4012: Integrated Pathology and Clinical Medicine Part 2 of 3 (Level 4; TSV)
  • MD4013: Integrated Pathology and Clinical Medicine Part 3 of 3 (Level 4; TSV)

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Sanofi Pasteur - Contract Research

Efficacy, Immunogenicity, and Safety Study of Clostridium difficile Toxoid Vaccine in Subjects at Risk for C. difficile Infection

Indicative Funding
$578,450 over 5 years
Clostridium difficile is a bacterial infection that can cause severe diarrhoea in people who have been exposed to the hospital environment and antibiotics. The bacteria produces a toxin, which is responsible for the clinical symptoms. Antibodies, induced by vaccination, may prevent the disease which is now amongst the leading cause of gastroenteritis in developed countries. This trial, which will enrolled 15,000 patients from around the world will measure the rate of clinical episodes of diarrhoea due to Clostridium difficile in people who have been vaccinated versus those who have received a placebo.
John McBride and Nichola Davis in collaboration with Sue Richmond (College of Medicine & Dentistry and Queensland Health)
Clostridium difficile; Vaccine; Clinical Trial

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