About

Dr. Paramjit was awarded Ph.D. by Guru Nanak Dev University- Amritsar, India. He has worked in many research areas in chemistry. In Australia he mainly did peptide synthesis. He was also a Senior Humboldt Research Fellow in W. Germany (1980-81). He worked in such diverse areas of chemistry such as synthesis of heterocyclics and macrocyclics, development of efficient drug delivery methods, synthesis of functionalized polymers to remove cholesterol from dairy and egg products and blood plasma, synthesis of deuterated molecules. His major area of research is synthesis of biologically active peptides from natural resources and engineering peptides to improve their activity and bioavailability. He also taught in chemistry department of GNDU-Amritsar, India for seven years as lecturer then as reader and supervised Ph.D., M.Phil., M.Sc. Students before migrating to Australia..

 

Experience
  • 2013 to present - Postdoc, JCU (Cairns)
  • 1980 to 198181 - Senior Alexander von Humboldt Fellow, Bielefeld University (West Germany)
  • 2008 to 2012 - Senior Research Scientist, ANSTO (Lucas Heights, NSW)
  • 2006 to 2008 - Research Fellow, Sydney University (Camperdown, Sydney)
  • 1998 to 2006 - Senior Research Officer, St. LuciaUniversity of Queensland (IMB)
  • 1995 to 1998 - Senior Research Scientist, Sugar Research Institute (Mackay, Qld)
  • 1992 to 1995 - Research Scientist, CSIRO (North Ryde, NSW)
  • 1990 to 1992 - Research Officer, University of Queensland (3D Centre)
  • 1988 to 1990 - Research Associate, Adelaide University (Chemistry dept.)
  • 1981 to 1987 - Lecturer/Reader, GNDU-Amritsar, India (Chemistry Dept.)
Socio-Economic Objectives
Honours
Fellowships
  • 1980 to 1981 - Senior Alexander von Humboldt Research Fellow.
Memberships
  • 2000 - Fellow of Royal Australia Chemical Institute
  • 1976 - Life member of Indian Chemical Society
Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles
Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

Merchant Charitable Foundation - Donation

Pre-clinical development of a liver fluke growth factor for treating non-healing wounds

Indicative Funding
$150,000
Summary
This research proposal aims to develop more effective treatments for wound healing, improving treatment options for diabetic patients in Australia and eventually worldwide. This is likely to alleviate suffering from the disease and also decrease the AUD$3.6 billion financial burden of diabetic wound ulcers on the healthcare system. Although we showed that the liver fluke granulin protein has wound healing properties, it is difficult to produce in recombinant form. We have now developed a minimized version of granulin and produce it as a synthetic peptide that when applied topically displays wound-healing properties as potent as the full-length protein. Using the peptide as a topical agent is ideal because it capitalizes on the potency and specificity often associated with peptide-based drugs but does not require the high levels of bioavailability necessary for orally administered drugs. Our research will also provide advances in the field regarding the structure and folding of Ov-GRN-1, which will be of significant interest to researchers working specifically on growth factors and more broadly for those working on disulphide-rich peptides and proteins. Moreover, we believe that our decision to be guided in drug discovery by millennia of host-parasite coevolution will ensure that the most efficacious and safe drugs are identified and developed.
Investigators
Alex Loukas, Michael Smout, Norelle Daly and Paramjit Bansal (Australian Institute of Tropical Health & Medicine)
Keywords
Liver Fluke; Growth Factor; Wound Repair; Therapeutics; Diabetes
Supervision

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These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current
  • Development of Disulfide-Rich Peptides as Potential Drug Leads. (PhD , Secondary Advisor)
Collaboration

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  • 5+ collaborations
  • 4 collaborations
  • 3 collaborations
  • 2 collaborations
  • 1 collaboration
  • Indicates the Tropics (Torrid Zone)

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