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Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles
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ResearchOnline@JCU stores 111+ research outputs authored by Prof Reinhold Muller from 2001 onwards.

Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

NHMRC - Project Grant

Telmisartan in the management of abDominal aortic aneurYsm (TEDY)

Indicative Funding
$1,105,894 over 5 years
Summary
Approximately 5% of men and 1% of women aged over 60 years develop weakening of the main abdominal artery. Currently the management of artery weakening is focused on surgery with no effective medications available. In this trial we will examine the value of a promising drug therapy. If proved effective this medication could reduce the requirement for surgery by controlling artery weakening at an early stage in its development.
Investigators
Jonathan Golledge, Paul Norman, Phillip Walker, Anna Ahimastos, Ronald Dalman, Robert Fitridge, Andrew Tonkin, Christopher Reid, Reinhold Muller, Frank Quigley, Graeme Hankey, Bernard Bourke, Anthony Dear and Bronwyn Kingwell (College of Medicine & Dentistry, The University of Western Australia, The University of Queensland, Baker Heart & Diabetes Institute, Stanford University, University of Adelaide, Monash University, College of Public Health, Medical & Vet Sciences and Gosford Hospital)
Keywords
Abdominal aortic aneurysm; Pathogenesis; thrapy; Patient management; Peripheral vascular disease; Cardiovascular Diseases

NHMRC - Project Grant

Interaction between parathyroid hormone, sclerostin and the wingless pathway in abdominal aortic aneurysm

Indicative Funding
$698,300 over 5 years
Summary
Approximately 5% of men and 1% of women aged over 60 years develop weakening of the main abdominal artery. Currently the management of artery weakening is focused on surgery with no effective medications available. In this study we will assess the role of a novel pathway in artery weakening. Improved understanding of the mechanisms causing artery degeneration is crucial to target the development of better ways to treat this common problem.
Investigators
Jonathan Golledge, Paul Norman, Catherine Rush, Phillip Walker, Craig Jeffrey, Reinhold Muller, Anthony Dear, Timothy Buckenham and Gabby Loots (College of Medicine & Dentistry, The University of Western Australia, College of Public Health, Medical & Vet Sciences, The University of Queensland, Monash University, Christchurch Hospital and Lawrence Livermore National Laboratory)
Keywords
Abdominal aortic aneurysm; Pathogenesis; Therapy; Patient management; Peripheral vascular disease; Cardiovascular Diseases

NHMRC - Project Grant

The role of the clotting cascade in aortic aneurysm and associated cardiovascular events

Indicative Funding
$619,911 over 5 years
Summary
Weakening of the main abdominal artery is responsible for approximately 100 deaths/ year in Australia. Most weakened arteries are identified at an early stage but there is no current therapy which limits the progression of artery weakening. There is also no model which predicts the complications associated with weakened arteries. In the current project we proposed the importance of clot in progression and complications of weakened arteries. We will undertake studies to identify new therapies and a predictive model for weakened arteries.
Investigators
Jonathan Golledge, Catherine Rush, Phillip Walker, Robert Fitridge, Reinhold Muller, Corey Moran and Paula Clancy in collaboration with Robert Andrews, Lajos Gera, Benjamin Herbert, Katherine High, Paul Norman, Thomas Renne and Douglas Tollefsen (College of Medicine & Dentistry, College of Public Health, Medical & Vet Sciences, The University of Queensland, QEII Jubilee Hospital, Monash University, University of Colorado - Boulder, Macquarie University, Academy of National Sciences of Philadelphia, The University of Western Australia, Karolinska Institute and Washington University in St. Louis)
Keywords
Cardiovascular Diseases; Thrombosis; Abdominal aortic aneurysm; Biological Markers; Thrombin
Supervision

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These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current
  • Integration of medical circumcision within re-established manhood rites for HIV prevention in Yangoru-Saussia, Papua New Guinea (PhD , Secondary Advisor/AM)
Completed
Collaboration

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.

  • 5+ collaborations
  • 4 collaborations
  • 3 collaborations
  • 2 collaborations
  • 1 collaboration
  • Indicates the Tropics (Torrid Zone)

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