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Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

National Health & Medical Research Council - Development Grant

Hookword peptide therapeutic for oral treatment of IBD

Indicative Funding
$732,700 over 2 years
Summary
We intend to develop an orally delivered peptide that can modulate the immune system and be developed as a therapeutic for inflammatory bowel disease. We have identified a peptide, derived from a hookworm protein, that alleviates the clinical symptoms of experimental colitis when orally administered to mice. The peptide has bioactivity with human cells ex vivo and displays desirable drug-like properties. The aim of this project is to acquire further data on the mechanism of action and formulation conditions to facilitate formal product development prior to licensing and clinical trials.
Investigators
Alex Loukas, Norelle Daly, Paul Giacomin, John Miles, Roland Ruscher, Keith Dredge, Istvan Toth, Mariusz Skwarczynski, Matthew Moyle, Ashley Waardenberg, John Croese, Matt Field and Tony Rahman (Australian Institute of Tropical Health & Medicine, The University of Queensland and The Prince Charles Hospital)
Keywords
Inflammatory Bowel Disease; Peptide; therapeutic; Hookworm; Oral delivery
Supervision

Advisory Accreditation: I can be on your Advisory Panel as a Secondary Advisor.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current
  • Biodiscovery of anti-inflammatory drug leads from parasites and medicinal plants of Australian wet tropics. (PhD , Secondary Advisor)
  • Structure and Function of Novel Peptides from Cone Snail Venom (PhD , Secondary Advisor)
Collaboration

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.

  • 5+ collaborations
  • 4 collaborations
  • 3 collaborations
  • 2 collaborations
  • 1 collaboration
  • Indicates the Tropics (Torrid Zone)

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Similar to me

  1. Dr Paul Giacomin
    Australian Institute of Tropical Health & Medicine
  2. Mr Darren Pickering
    Australian Institute of Tropical Health & Medicine
  3. Dr Severine Navarro
    Australian Institute of Tropical Health & Medicine
  4. Prof Alex Loukas
    Australian Institute of Tropical Health & Medicine
  5. Prof Norelle Daly
    Australian Institute of Tropical Health & Medicine