Dr Shiv Thanigaimani ~ Research Fellow, Peripheral Vascular Disease (PVD)

Biography:

I was trained in biotechnology at Flinders University and received Ph.D. in Medicine from the University of Adelaide after completing a research program investigating reverse atrial remodeling in a hypertensive large animal model. I continued to explore the prevention of atrial remodeling with small animal models during my work as a postdoctoral fellow. Later, I joined as a postdoctoral research scientist at the Queensland Research Centre for Peripheral Artery Diseases. In 2023, I was promoted as Research fellow (Peripheral vascular disease).

Research:

My broad research interests span within vascular biology, specifically in understanding the risk factors and mechanisms of peripheral artery diseases. I primarily perform pre-clinical and in vitro studies involving development of PAD animal models via microsurgery, and a number of secondary assays. Clinically, I am involved in determining risk factors of PAD through various statistical modeling and techniques using prospectively collected patient data. My research aim is to enable direct translation of my work towards improving PAD patient management.

I would welcome any inquiries from students interested in gaining research experience or undertaking honors or PhD research projects in topics including abdominal aortic aneurysm, limb ischemia and limb ulcers.

Scientific contribution:

International advisory board member - CIMSER, Loyola college, India.

Grant reviewer - Diabetes Australia.

Editorial board member - BMC cardiovascular discorders, BMC research notes, Cardiovascular therapeutics.

Review editor - Frontiers (General Cardiovascular Medicine, Atherosclerosis and Vascular Medicine, Aortic surgery and endovascular repair).

Peer reviewer - International Journal of Medical Sciences (IJMS), Cells, Journal of Clinical Medicine (JCM), Current Molecular Medicine (CMM), Current Vascular Pharmacology (CVP) and Molecules.

Interests

Professional

• Vascular biology

Research

• Abdominal aortic aneurysm
• Limb ischemia
• Statistical genomics & biostatistics

Experience

• 2023 to present - Research fellow, James Cook University (Australia)
• 2019 to 2022 - Postdoctoral Research Scientist, James Cook University (Australia)
• 2016 to 2018 - Postdoctoral fellow, University of Adelaide (Australia)
• 2014 to 2016 - Research Assistant, University of Adelaide (Australia)

Research Disciplines

• Cardiovascular medicine and haematology (3201)

Socio-Economic Objectives

• Clinical health (2001)

Awards

• 2016 - Second prize: Young Investigator award – Asia Pacific Heart rhythm society. Seoul, South Korea
• 2016 - Finalist: Ralph reader prize – Cardiac Society of Australia and New Zealand. Adelaide, Australia
• 2015 - Winner: Victorian government educational grant allowance ($1,000) – Asia Pacific Heart rhythm society. Melbourne, Australia.
• 2015 - Finalist: Young Investigator award – Asia Pacific Heart rhythm society. Melbourne, Australia
• 2014 - Dean’s commendation for doctoral thesis excellence: University of Adelaide
• 2014 - Finalist: Best oral presentation Asia Pacific Heart rhythm society. New Delhi, India

Memberships

• 2021 - Queensland Cardiovascular Research Network

Other

• 2022 - Incentive grant ($4500), College of Medicine & Dentistry, James Cook University
• 2016 - Discipline of Medicine Travel grant ($2,000), The University of Adelaide
• 2013 - Discipline of Medicine Travel grant ($2,000), The University of Adelaide
• 2011 to 2014 - Peter Hetzel electrophysiology scholarship ($122,500 for 3.5 years)
• 2011 to 2014 - The University of Adelaide full fee waiver scholarship ($98,000 for 3.5 years)

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles

• Golledge J and Thanigaimani S (2022) Role of Sclerostin in Cardiovascular Disease. Arteriosclerosis, Thrombosis and Vascular Biology, 42. pp. e187-e202
• Matthews E, Moxon J, Singh T, Thanigaimani S, Jones R, Gasser T, Fitridge R, Lindeman J, Dalman R and Golledge J (2022) Athero-occlusive disease appears to be associated with slower abdominal aortic aneurysm growth: an exploratory analysis of the TEDY trial. European Journal of Vascular and Endovascular Surgery, 63 (4). pp. 632-640
• Phie J, Thanigaimani S, Huynh P, Anbalagan R, Moran C, Kinobe R, Moxon J, Field M, Krishna S and Golledge J (2022) Colchicine Does Not Reduce Abdominal Aortic Aneurysm Growth in a Mouse Model. Cardiovascular Therapeutics, 2022.
• Thanigaimani S, Phie J, Quigley F, Bourke M, Bourke B, Velu R, Jenkins J and Golledge J (2022) Immunosuppressive drugs for nontransplant comorbidities are not associated with abdominal aortic aneurysm growth. JVS: Vascular Science, 3. pp. 306-313
• Thanigaimani S, Ibrahim M and Golledge J (2022) Potential of Disease-Modifying Anti-Rheumatic Drugs to Limit Abdominal Aortic Aneurysm Growth. Biomedicines, 10 (10).
• Thanigaimani S, Jin H, Silva M and Golledge J (2022) Network Meta-Analysis of Trials Testing If Home Exercise Programs Informed by Wearables Measuring Activity Improve Peripheral Artery Disease Related Walking Impairment. Sensors, 22 (20).
• Thanigaimani S, Phie J, Quigley F, Bourke M, Bourke B, Velu R, Jenkins J and Golledge J (2022) Association of Diagnosis of Depression and Small Abdominal Aortic Aneurysm Growth. Annals of Vascular Surgery, 79. pp. 256-263
• Thanigaimani S, Drovandi A and Golledge J (2022) A meta-analysis of randomised controlled trials evaluating the efficacy of smoking cessation interventions in people with peripheral artery disease. Journal of Vascular Surgery, 75 (2). pp. 721-729.e7
• Golledge J and Thanigaimani S (2021) Novel therapeutic targets for diabetes-related wounds or ulcers: an update on preclinical and clinical research. Expert Opinion on Therapeutic Targets, 25 (12). pp. 1061-1075
• Golledge J, Thanigaimani S and Phie J (2021) A systematic review and meta-analysis of the effect of pentagalloyl glucose administration on aortic expansion in animal models. Biomedicines, 9 (10).
• Ibrahim M, Thanigaimani S, Singh T, Morris D and Golledge J (2021) Systematic review and meta-analysis of Mendelian randomisation analyses of abdominal aortic aneurysms. IJC Heart and Vasculature, 35.
• Lim W, Neo M, Thanigaimani S, Kuklik P, Ganesan A, Lau D, Tsoutsman T, Kalman J, Semsarian C and Saint D (2021) Electrophysiological and structural remodeling of the atria in a mouse model of troponin-i mutation linked hypertrophic cardiomyopathy: Implications for atrial fibrillation. International Journal of Molecular Sciences, 22 (13).

More

ResearchOnline@JCU stores 29+ research outputs authored by Dr Shiv Thanigaimani from 2011 onwards.

Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current

• Developing a Risk Score to predict the Risk of Major Adverse Cardiovascular events in Patients with Abdominal Aortic Aneurysm (Masters , Secondary Advisor)

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.