About

Dr Karl has a M. Sc. in Biological Process Engineering (2007) and a PhD in biophysics (University of Western Australia, 2012). He has done postdocs in vector-borne diseases epidemiology and entomology at Walter and Eliza Hall Institute , James Cook University and PNG Institute of Medical Research. He is currently a Senior Research Officer in the Australian Institute of Tropical Health and Medicine at JCU and laboratory head of the entomology section at the PNG Institute of Medical Research. He has 65 research papers mainly in the field of vector-borne tropical diseases, a 14 year collaborative history with the PNG Institute of Medical Research and more than 5 years of full-time in-country research experience in PNG.

Dr Karl is currently a project leader in the NIH-funded Asia-Pacific Centre of Excellence in Malaria Research in PNG (2017-2023) and a program director in an Australian Department of Foreign Affairs and Trade-funded program to strengthen surveillance and control of malaria and arboviruses in PNG (Strive PNG, 2018-2020). Dr Karl is also leading the Global Fund to Fight Aids, Malaria and Tuberculosis-funded mosquito monitoring activities in PNG (since 2017) as well as various studies funded by the Bill and Melinda Gates Foundation, Australian National Health and Medical Research Council and the Commonwealth Scientific and Industrial Research Organisation.

Research Disciplines
Socio-Economic Objectives
Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles
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ResearchOnline@JCU stores 68+ research outputs authored by A/PROF Stephan Karl from 2010 onwards.

Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

National Health & Medical Research Council - Centres of Research Excellence - ACE - NTD - Small Grant

Mapping of Lymphatic Filariasis (LF) Prevalence in Papua New Guinea (PNG).

Indicative Funding
$35,000 over 2 years (administered by University of New South Wales)
Summary
Malaria and LF are co-endemic and transmitted by the same vectors in PNG. It is likely that integrated surveillance and control approaches are effective to reduce the burden of both diseases synergistically. The aim of the proposed study is to utilize samples collected in the most recent malaria indicator survey (MIS) in 22 PNG provinces to gain a better understanding about LF prevalence and distribution in the country. The result will be an LF prevalence map and spatial risk model to guide planning of LF surveillance, control and elimination. The spatial LF data will be complemented with in-depth surveys in key locations and detailed spatial vector control coverage data already collected in the MIS or provided by our partners.
Investigators
Stephan Karl, Leanne Robinson, Maria Ome-Kaius, Christopher King, Moses LAMAN, Manuel Hetzel, Colleen Lau and William Pomat (Australian Institute of Tropical Health & Medicine, Institute of Medical Research (PNG), Case Western Reserve University, Papua New Guinea Institute of Medical Research, Swiss Tropical & Public Health Institute and The University of Queensland)
Keywords
Lymphatic Filariasis; malaria; mosquitoes; vector; Mapping

National Health & Medical Research Council - Ideas Grants

Substandard bed nets and malaria: Causes, Impact and Solutions

Indicative Funding
$827,057 over 4 years
Summary
Long-lasting insecticidal nets (LLIN) are a cornerstone of malaria control. LLIN undergo strict testing overseen by WHO and are subject to inspections prior to delivery to recipient countries. Despite this, we found that LLINs delivered to Papua New Guinea (PNG) between 2013 and 2019 were unable to kill malaria mosquitos. Concurrently we observed a massive increase in malaria in PNG. This study is aimed at understanding the causes and impact of substandard LLINs on the global malaria burden.
Investigators
Stephan Karl, Norelle Daly, Ellie Sherrard-Smith, Jeremy Bougoure, Michael White, Lisa Reimer and Moses LAMAN in collaboration with Leanne Robinson, Ivo Mueller, Thomas Churcher, Julie Healer, Amelie Vantaux, David MacLaren and Tim Freeman (Australian Institute of Tropical Health & Medicine, Imperial College London, University of Western Australia, Institut Pasteur, Liverpool School of Tropical Medicine, Institute of Medical Research (PNG), Burnet Institute, Walter & Eliza Hall Institute of Medical Research, Institut Pasteur du Cambodge and Rotarians Against Malaria PNG)
Keywords
Papua New Guinea; Malaria; Bed Nets; Bioefficiency; Anopheles

Rotary Australia - Rotarians Against Malaria

PNG National Malaria Control Program Long-lasting Insecticidal Net Quality Assurance Support

Indicative Funding
$55,766 over 1 year (administered by Rotarians Against Malaria PNG)
Summary
The project will provide long-lasting insecticidal net (LLIN) quality assurance (QA) support to the PNG National Malaria Control Program.
Investigators
Stephan Karl (Australian Institute of Tropical Health & Medicine)
Keywords
Malaria; Papua New Guinea; Quality Assurance; Long-lasting Insecticidal Nets

Vanilla Mozi Pty Ltd - Contract Research

Evaluation of insecticidal and repellency efficacy of Vanilla Mozi products (topical) against Aedes aegypti colony mosquitoes.

Indicative Funding
$9,750
Summary
This project is about testing the mosquito repellency of a topical lotion product manufactured by Vanilla Mozzi using colony Ae. aegypti mosquitoes.
Investigators
Melanie Koinari, Stephan Karl and Michael Townsend (Australian Institute of Tropical Health & Medicine)
Keywords
Mosquito Repellent; Aedes aegypt; Vanilla Mozi

CSIRO - Contract Research

Strengthened surveillance for vector-borne zoonotic and livestock diseases in Papua New Guinea.

Indicative Funding
$22,510 over 1 year (administered by Commonwealth Scientific & Industrial Research Organisation)
Summary
This proposed research will consolidate and build on previous research and pilot surveillance conducted on zoonotic arboviruses in PNG (SRA LS/2018/213) and will aim to continue and expand a One Health surveillance approach for Japanese encephalitis and zoonotic arboviruses in PNG. The overall objective of the project will be to combine mosquito, sentinel animal and human surveillance for JE and other zoonotic arboviruses to continue to build and consolidate capacity and expertise in this area, through a holistic, One Health approach.
Investigators
Stephan Karl in collaboration with Paul Horwood and Melanie Koinari (Australian Institute of Tropical Health & Medicine, College of Public Health and Medical & Vet Sciences)
Keywords
Japanese Encephalitis; Zoonotic; Papua New Guinea; Vector surveillance; arbovirus; agriculture

Macfarlane Burnet Institute for Medical Research and Public Health - Contract Research

Newly adopted tools and network against disease transmission (NATNAT).

Indicative Funding
$1,010,943 over 4 years
Summary
The proposed consortia and the NATNAT project, will support the Papua New Guinea Institute of Medical Research (PNGIMR) and PNG NDoH to adopt a 'framework for rapid assessment and adoption of new vector control tools' (VCTs) [1] for PNG and the South Pacific Region, including VCTs targeted at controlling Anopheline and Aedine populations.
Investigators
Stephan Karl in collaboration with Leanne Robinson and Moses LAMAN (Australian Institute of Tropical Health & Medicine, Burnet Institute and Institute of Medical Research (PNG))
Keywords
Capacity Building; Quality Control; Papua New Guinea; Education; Resistance; Empowerment

Department of Foreign Affairs and Trade (DFAT) - Pacific Infectious Disease Prevention (PIDP) Program

Building Capacity for Evidence Based Sustainable Vector Surveillance and Control in the Pacific.

Indicative Funding
$4,974,884 over 4 years
Summary
This proposal will build the capacity of country-led programs for Aedes and anopheline borne disease control across Pacific Island countries to implement sustainable best practice surveillance and response plans based on a foundation of improved capacity and community engagement.
Investigators
Tom Burkot, Tanya Russell, Stephan Karl, Kyran Staunton, Tessa Knox, Rabindra Abeyasinghe, Angela Merianos, Gregor Devine, Michael Nunan, Gerard Kelly, Lisa Natoli, Veronica Bell, Moses LAMAN, Adam Craig, Nigel Beebe and Leanne Robinson (Australian Institute of Tropical Health & Medicine, College of Public Health, Medical & Vet Sciences, World Health Organisation (Switzerland), QIMR Berghofer, Beyond Essential Systems, Red Cross Australia, Institute of Medical Research (PNG), University of New South Wales, The University of Queensland and Burnet Institute)
Keywords
Dengue; Aedes; Capacity Building; Ministry of Health; Pacific region; Anopheles

Department of Foreign Affairs and Trade (DFAT) - DFAT Stronger Systems For Health Security

Stronger surveillance and systems support for rapid identification and containment of resurgent or resistant vector borne pathogens in Papua New Guinea.

Indicative Funding
$121,016 over 4 years (administered by Burnet Institute)
Summary
This project is aimed at stronger surveillance and systems support for rapid identification and containment of resurgent or resistant vector borne pathogens in Papua New Guinea. The subcontract to JCU includes a specific work package on arbovirus and malaria mosquito surveillance.
Investigators
Leanne Robinson, Stephan Karl, Alyssa Barry, Nigel Beebe and Jack Richards in collaboration with Moses LAMAN, Ivo Mueller, Evelyn Lavu, Lucy John, Christopher Morgan, Freya Fowkes, David Williams, Leo Makita, Nakapi Tefuarani, Nick Scott, Paul Horwood, Qin Cheng, Richard Price, Tom Burkot and William Pomat (Burnet Institute, Papua New Guinea Institute of Medical Research, Walter & Eliza Hall Institute of Medical Research, Central Public Health Laboratory, National Department of Health (PNG), Australian Institute of Tropical Health & Medicine, The University of Queensland, Commonwealth Scientific & Industrial Research Organisation, University of Papua New Guinea, College of Public Health, Medical & Vet Sciences, Army Malaria Institute and Menzies Health Institute Queensland)
Keywords
Papua New Guinea; Health System Strengthening; Malaria; Arbovirus; Surveillance; Control

Rotary Australia - Rotarians Against Malaria

Investigating tramsmission of Malaria Parasites in Anopheles farauti Mosquitos in PNG. Lincoln Timinao?s PhD Stipend for 12 months.

Indicative Funding
$29,800 over 1 year
Summary
Lincoln Timinao?s scholarship for the duration of 12 months (approved PhD candidature extension). Lincoln?s project involves assessing the infectivity of malaria infected blood samples to Anopheles mosquitoes and exploring ways to block transmission from humans to mosquitoes.
Investigators
Stephan Karl in collaboration with Lincoln Timinao (Australian Institute of Tropical Health & Medicine)
Keywords
Malaria; Transmission blocking; Membrane feeding; Anopheles

Department of Industry - Innovations Connections

Testing of insecticidal and repellency

Indicative Funding
$49,214 over 1 year, in partnership with Australian Blue Cypress Pty Ltd ($49,214)
Summary
Testing the mosquito repellency of a topical lotion product manufactured by Australian Blue Cypress P/L (ABCPL) using colony Ae. aegypti mosquitoes in order to provide data for accreditation by the Australian pesticides and veterinary medicines authority (APVMA).
Investigators
Stephan Karl and Melanie Koinari (Australian Institute of Tropical Health & Medicine)
Keywords
Mosquito repellent; Aedes aegypti; Kakadu Blue

National Health & Medical Research Council - Career Development Fellowship

Plasmodium vivax transmission blocking studies in the South Pacific

Indicative Funding
$437,034 over 4 years
Summary
This project is aimed at better understanding transmission of P. vivax, the world's most widely spread malaria parasite. Using a newly established experimental platform that enables us to feed P. vivax infected blood to Anopheles farauti mosquitoes, we can start researching factors in human blood that determine P. vivax infection success, test new vaccine and drug candidates for their ability to block transmission and thus significantly advance science surrounding this neglected parasite.
Investigators
Stephan Karl in collaboration with Louis Schofield, Tom Burkot, Vicky Avery, Ivo Mueller and Laman Moses (Australian Institute of Tropical Health & Medicine, Griffith University, Walter & Eliza Hall Institute of Medical Research and Institute of Medical Research (PNG))
Keywords
Plasmodium Vivax; Anopheles Farauti; Malaria Vaccines; antimalarial drugs; transmission blocking immunity; Papua New Guinea

Australian Centre for International Agricultural Research - Research Grant

A one health approach to establish surveillance strategies for Japanese encephalitis and zoonotic arboviruses in Papua New Guinea

Indicative Funding
$23,700 over 2 years (administered by Commonwealth Scientific & Industrial Research Organisation)
Summary
The project aim is to establish surveillance for JEV and other zoonotic arboviruses that affect the rural population of PNG. The major objectives are to: 1. Evaluate current detection methods to detect zoonotic arboviruses in the field and laboratory, and build capacity where gaps are identified. 2. Establish surveillance at selected sites using sentinel animal (pigs, chickens) and mosquito trapping 3. Develop linkages and coordination between human and animal health agencies. The primary outputs are to develop surveillance activities that contribute to early warning for public health and provide a better understanding of the ecological drivers of arboviruses in PNG.
Investigators
David Williams, Leanne Robinson, Paul Horwood, Stephan Karl and Dagmar Meyer Steiger (Australian Centre for Disease Preparedness, Burnet Institute and Australian Institute of Tropical Health & Medicine)
Keywords
Japanese encephalitis virus; Arbovirus; Papua New Guinea; Mosquito; Vector; Zoonotic
Supervision

Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current
  • Modelling Dengue transmission: forecast models, mapping and simulations to estimate the impact of public health interventions on global Dengue burden (PhD , Secondary Advisor)
  • Effect of alternative Vector Control Strategies on Vector Ecology in Papua New Guinea (PhD , Primary Advisor/AM/Adv)
  • Efficacy of long-lasting Insecticidal Nets and alternative Vector Control strategies against Malaria and Dengue Mosquitoes in the South-Pacific region (PhD , Primary Advisor)
  • Evaluation of Spatial Repellent products against Malaria Vector Species in Papua New Guinea (PhD , Primary Advisor)
Completed
Collaboration

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.

  • 5+ collaborations
  • 4 collaborations
  • 3 collaborations
  • 2 collaborations
  • 1 collaboration
  • Indicates the Tropics (Torrid Zone)

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  3. Dr Melanie Koinari
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  4. Prof Tom Burkot
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  5. Dr Kyran Staunton
    Australian Institute of Tropical Health & Medicine