JCU > Research Portfolio > Dr Tejas Singh

About

Dr Tejas P Singh is a Junior Doctor at The Townsville Hospital and a Research Fellow at the Queensland Research Centre for Peripheral Vascular Disease (QRCPVD) at the School of Medicine and Dentistry, James Cook University. After graduating from a Bachelor of Medicine, Bachelor of Surgery, Dr Singh completed a Masters of Public Health and is currently undertaking a Doctor of Philosophy at James Cook University. Dr Singh’s research commitment is illustrated by multiple publications in high-impact peer reviewed journals and numerous presentations at international and national level conferences. Dr Singh aspires to provide quality clinical care to patients with vascular diseases and contribute research aimed at improving the management of peripheral vascular diseases. Dr Singh has been awarded multiple grants from a range of organisations including the Queensland Government. Of note, in 2017 Dr Singh was awarded a research fellowship from the Queensland Government valued at $250,000 to support his research aimed at investigating novel methods of estimating prognosis for patients with abdominal aortic aneurysms.

Research/Projects:

Identifying novel drug, diagnostic and prognostic targets for peripheral arterial diseases and associated cardiovascular complications.
Evaluating the prognostic utility of biomechanical estimates of wall stress for abdominal aortic aneurysms.
Investigating the presenting characteristics and clinical outcomes of Indigenous Australians with peripheral arterial disease.
Investigating the clinical utility of blood markers to monitor progress and treatment efficacy in peripheral arterial disease.
Development and validation of a novel angiographic scoring system for peripheral arterial disease.
Investigating the association of Computed Tomographic lower limb muscle characteristics with lower limb and cardiovascular events in patients with peripheral artery disease.

Interests

Research

abdominal aortic aneurysm, peripheral arterial disease, diabetic foot ulcer

Experience

2018 to present - Research Fellow, Queensland Research Centre for Peripheral Vascular Disease, College of Medicine and Dentistry, James Cook University (Townsville)
2019 - Principal House Officer, Vascular Surgery, The Townsville Hospital (Townsville)
2018 - Moderator for Plenary session, 3rd Edition of World Congress & Exhibition on Vascular Surgery (London, UK)
2018 - Resident Medical Officer, Vascular Surgery, The Townsville Hospital (Townsville)
2017 to 2018 - Graduate Diploma of Anatomy, Macquarie University (NSW)
2017 to 2018 - Medical Internship, The Townsville Hospital (Townsville)
2017 - Reviewer, BMC Cardiovascular Disorders
2016 to 2017 - Master of Public Health, University of Queensland (Brisbane)
2016 to 2017 - Senior Associate Editor, Australian Medical Student Journal (AMSJ)
2011 to 2016 - Bachelor of Medicine, Bachelor of Surgery, James Cook University (Townsville)

Research Disciplines

Socio-Economic Objectives

Honours

Awards

2018 to 2020 - The Townsville Hospital SERTA grant. Assessment of the efficacy of a novel treatment for Peripheral Artery Disease (PAD). $50,000. Golledge J, Moxon JV, Singh TP, Wong R, Sangla K, White V.
2018 to 2019 - The Townsville Hospital SERTA grant. Peak Wall Stress as a prognostic indicator of Abdominal Aortic Aneurysm rupture risk. $50,000. Singh TP, Golledge J, Moxon J, Gasser C.
2017 to 2018 - The Townsville Hospital SERTA grant. Presentation and outcomes of Indigenous Australians with peripheral artery disease. $40,000. Singh TP, Golledge J, Moxon J, Cadet-James, Y
2015 - Conference presentation support from JCU. College of Medicine & Dentistry.
2014 - First Wave GPSN Scholarship. $300.

Fellowships

2018 to 2020 - Junior Doctor Research Fellowship, Queensland Health (HIIRO). $250,000

Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles

Golledge J and Singh T (in press) Effect of blood pressure lowering drugs and antibiotics on abdominal aortic aneurysm growth: a systematic review and meta-analysis. Heart, , DOI:10.1136/heartjnl-2020-318192.
Singh T, Moxon J, Gasser T and Golledge J (2021) Systematic review and meta-analysis of peak wall stress and peak wall rupture index in ruptured and asymptomatic intact abdominal aortic aneurysms. Journal of the American Heart Association, 10 (8), Article: e019772, DOI:10.1161/JAHA.120.019772.
Singh T, Moxon J, Meehan M, Jones R, Cadet-James Y and Golledge J (2021) Major amputation rates and outcomes for Aboriginal and Torres Strait Islander and non-Indigenous people in North Queensland Australia between 2000 and 2015. BMC Endocrine Disorders, 21 (1), Article: 101, DOI:10.1186/s12902-021-00764-z.
Singh T, Moxon J, Iyer V, Gasser T, Jenkins J and Golledge J (in press) Comparison of peak wall stress and peak wall rupture index in ruptured and asymptomatic intact abdominal aortic aneurysms. British Journal of Surgery, , DOI:10.1002/bjs.11995.
Thanigaimani S, Singh T, Unosson J, Phie J, Moxon J, Wanhainen A and Golledge J (2021) Association between metformin prescription and abdominal aortic aneurysm growth and clinical events: a systematic review and meta-analysis. European Journal of Vascular and Endovascular Surgery, 62 (5), pp. 747-756, DOI:10.1016/j.ejvs.2021.06.013.
Thanigaimani S, Singh T and Golledge J (in press) Topical oxygen therapy for diabetes?related foot ulcers: a systematic review and meta?analysis. Diabetic Medicine, , Article: e14585.
Drovandi A, Fernando M, Singh T, Woolley T and Golledge J (2020) Opinions of vascular surgeons and podiatrists in Australia and New Zealand on the use of hyperbaric oxygen therapy for lower limb ulcers. BMJ Open Diabetes Research & Care, 8, Article: e001590, DOI:10.1136/bmjdrc-2020-001590.
Golledge J, Pinchbeck J, Tomee S, Rowbotham S, Singh T, Moxon J, Jenkins J, Lindeman J, Dalman R, McDonnell L, Fitridge R, Morris D and TEDY Investigators (2020) Efficacy of Telmisartan to slow growth of small abdominal aortic aneurysms: a randomized clinical trial. Jama Cardiology, 5 (12), pp. 1374-1381, DOI:10.1001/jamacardio.2020.3524.
Golledge J, Moxon J, Singh T, Bown M, Mani K and Wanhainen A (2020) Lack of an effective drug therapy for abdominal aortic aneurysm. Journal of Internal Medicine, 288 (1), pp. 6-22, DOI:10.1111/joim.12958.
Singh T, Wong S, Quigley F, Jenkins J and Golledge J (2020) Association of gout with major adverse cardiovascular events and all-cause mortality in patients with peripheral artery disease. Atherosclerosis, 312, pp. 23-27, DOI:10.1016/j.atherosclerosis.2020.08.029.
Golledge J and Singh T (2019) Systematic review and meta-analysis of clinical trials examining the effect of hyperbaric oxygen therapy in people with diabetes-related lower limb ulcers. Diabetic Medicine, 36 (7), pp. 813-826, DOI:10.1111/dme.13975.

Book Chapters

Moxon J, Krishna S, Singh T and Golledge J (2020) Abdominal aortic aneurysm pathology and progress towards a medical therapy. In: Mechanisms of Vascular Disease: a textbook for vascular specialists. Springer, Cham, Switzerland, pp. 263-291

Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

Townsville Hospital and Health Service - Study Education Research Trust Account (SERTA)

Peak Wall Stress as a prognostic indicator of abdominal Aortic Aneurysm rupture risk

Indicative Funding: $50,000 over 3 years
Summary: Abdominal Aortic Aneurysm (AAA) affects 20 million people worldwide and 100,000 people in Australia. Annually, AAA rupture leads to 200,000 deaths worldwide and 2000 deaths in Australia. In clinical practice, maximum AAA diameter is the preferred surrogate measure for disease progression and rupture risk, and is used to guide surgical intervention. Approximately 10% of AAAs will rupture before they reach the current threshold for repair, whereas 60% of large AAAs remain stable during their lifetime, suggesting that diameter alone is an imperfect tool to decide which AAAs require surgical intervention. The specific aims of the project are Aim 1: To investigate if PWS is greater in patients with ruptured compared to intact AAAs matched for diameter; Aim 2: To evaluate the impact of a common anti-hypertensive medication {Telmisartan) on PWS and rupture risk in patients with small AAAs.
Investigators: Tejas Singh, Jon Golledge and Joseph Moxon in collaboration with Thomas Gasser (College of Medicine & Dentistry and Royal Institute of Technology)
Keywords: Metformin; Abdominal Aortic Aneurysm; Ruptures

Townsville Hospital and Health Service - Study Education Research Trust Account (SERTA)

Assessment of the efficacy of a novel treatment for Peripheral Artery Disease (PAD)

Indicative Funding: $50,000 over 3 years
Summary: Blockage of leg arteries (peripheral artery disease - PAD) leads to severe exertional leg pain (intermittent claudication), impaired walking ability, reduced health-related quality of life, and high risk of amputation and death. Multiple lines of evidence suggest that metformin, a cheap and safe medication, promotes formation of new vessels, improves microcirculation and muscle function,s and limits pain.
Investigators: Jon Golledge, Joseph Moxon, Tejas Singh, Rachel Wong, Kunwargit Sangla and Veronica White (College of Medicine & Dentistry and Townsville Hospital and Health Services)
Keywords: Metformin; peripheral artery disease; Intermittent Claudication

Collaboration

The map shows research collaborations by institution from the past 7 years.
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