Dr Thaddeus Wu ~ Lecturer, Computational Biologist / Bioinformatics Data Scientist

Dr Wu joined James Cook University in July 2022 as an Early Career Postdoctoral Researcher in A/Prof. Ulf Schmitz's team. Additionally, he holds the position of Lecturer in Mathematical and Computational Biology in the Department of Molecular & Cell Biology (CPHMVS). 

Thaddeus earned his PhD in Applied Mathematics from Monash University in March 2022. He conducts research in mathematical and computational biology, utilising his experience in mathematical modelling, algorithm development, and statistical analysis to study the mechanisms of cell fate determination. 

Currently, Thaddeus is focused on developing a novel mathematical framework to describe how mechanisms of alternative splicing and isoform expression at the single-cell level regulate cell fate determination.

Available HDR Student Projects

• Mathematical Modelling of Alternative Splicing and Transcriptomic Complexity
• Mathematical Modelling of Cell-Fate Determination

Teaching

• BC5203: Advanced Bioinformatics (Level 5; TSV)

Interests

Research

• Mathematical Modelling
• Stochastic Modelling
• Dynamic Systems
• Mathematical and Computational Biology
• Systems Biology

Experience

• 2022 to present - Postdoctoral Researcher and Lecturer, James Cook University (Townsville)

Research Disciplines

• Bioinformatics and computational biology (3102)
• Applied mathematics (4901)

Socio-Economic Objectives

• Expanding knowledge (2801)

Memberships

• 2022 - IEEE International Conference on Bioinformatics and Biomedicine Program committee
• 2022 - Australian Mathematical Society
• 2022 - Centre for Tropical Bioinformatics and Molecular Biology

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles

• Wu S and Schmitz U (2023) Single-cell and long-read sequencing to enhance modelling of splicing and cell-fate determination. Computational and Structural Biotechnology Journal, 21. pp. 2373-2380
• Wu S, Zhou T and Tian T (2022) A robust method for designing multistable systems by embedding bistable subsystems. npj Systems Biology and Applications, 8 (10).
• Wu S, Cui T, Zhang X and Tian T (2020) A non-linear reverse-engineering method for inferring genetic regulatory networks. PeerJ, 8.

Conference Papers

• Wu S, Cui T and Tian T (2019) Mathematical Modelling of Genetic Network for Regulating the Fate Determination of Hematopoietic Stem Cells. Proceedings of the IEEE International Conference on Bioinformatics and Biomedicine. In: BIBM 2018: IEEE International Conference on Bioinformatics and Biomedicine, 3-6 December 2018, Madrid, Spain