Prof Brian Cooke ~ Adjunct Professor
Australian Institute of Tropical Health & Medicine
- About
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- Research Disciplines
- Socio-Economic Objectives
- Publications
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These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.
- Journal Articles
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- Silva M, Bastos R, Laughery J, Alzan H, Rathinasamy V, Cooke B and Suarez C (2023) Vaccination of cattle with the Babesia bovis sexual-stage protein HAP2 abrogates parasite transmission by Rhipicephalus microplus ticks. NPJ Vaccines, 8.
- Bastos R, Alzan H, Rathinasamy V, Cooke B, Dellagostin O, Barletta R and Suarez C (2022) Harnessing Mycobacterium bovis BCG Trained Immunity to Control Human and Bovine Babesiosis. Vaccines, 10 (1).
- Alzan H, Bastos R, Ueti M, Laughery J, Rathinasamy V, Cooke B and Suarez C (2021) Assessment of Babesia bovis 6cys A and 6cys B as components of transmission blocking vaccines for babesiosis. Parasites and Vectors, 14.
- Florin-Christensen M, Schnittger L, Bastos R, Ambothi Rathinasamy V, Cooke B, Alzan H and Suarez C (2021) Pursuing effective vaccines against cattle diseases caused by apicomplexan protozoa. CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources, 16 (24).
- Siddiqui G, Proellochs N and Cooke B (2020) Identification of essential exported Plasmodium falciparum protein kinases in malaria-infected red blood cells. British Journal of Haematology, 188 (5). pp. 774-783
- Gallego-Lopez G, Cooke B and Suarez C (2019) Interplay between attenuation- and virulence-factors of Babesia Bovis and their contribution to the establishment of persistent infections in cattle. Pathogens, 8 (3).
- Other research outputs
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- Hemphill A, Leitão A, Ortega-Mora L and Cooke B (2023) ApicoWplexa 2022: 6th international meeting on apicomplexan parasites in farm animals. International Journal for Parasitology, 53. pp. 459-461
- Current Funding
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Current and recent Research Funding to JCU is shown by funding source and project.
International Development Research Centre - Livestock Vaccine Innovation fund
Development and deployment of a subunit vaccine against bovine babesiosis
- Indicative Funding
- $1,617,074 over 3 years
- Summary
- Bovine babesiosis caused by Babesia bovis is a tick?transmitted disease that causes severe, often fatal disease in cattle, resulting in significant economic losses to beef and dairy industries worldwide, as well as to individuals and small subsistence farmers in endemic areas. This project aims to make a dual?acting, subunit vaccine against babesiosis that is practical and easily deployable in babesiaendemic regions worldwide to prevent both acute disease in infected animals and parasite transmission by tick vectors. Farmers will benefit by protecting their animals against bovine babesiosis and achieve improved livestock production to meet local and global demand for animal products.
- Investigators
- Brian Cooke, Carlos Suarez and Vignesh Rathinasamy (Australian Institute of Tropical Health & Medicine, United States Department of Agriculture and Monash University)
- Keywords
- Babesia bovis; Babesia bigemina
Australian Research Council - Discovery - Projects
Understanding Babesia Pathogenesis
- Indicative Funding
- $179,406 over 4 years (administered by University of Technology Sydney)
- Summary
- This project aims at gaining a deep understanding of the biology of Babesia parasites and how they cause disease (bovine babesiosis) in cattle. The project expects to discover novel parasite proteins involved in the development and persistence of bovine babesiosis and identify their functional role in infection. The main expected outcome is the discovery of parasite proteins that are critical for infection and pathogenesis of bovine babesiosis. The outputs from this project will aid in the development of novel vaccines to control bovine babesiosis and such vaccines would significantly improve beef and dairy production worldwide.
- Investigators
- Brian Cooke, John Ellis and Carlos Suarez (Australian Institute of Tropical Health & Medicine, University of Technology Sydney and US Department of Agriculture - Forest Service)
- Keywords
- babesia bovis; babesia bigemina
- Collaboration
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The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.- 5+ collaborations
- 4 collaborations
- 3 collaborations
- 2 collaborations
- 1 collaboration
- Indicates the Tropics (Torrid Zone)
My research areas
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