A/Prof Haleagrahara Nagaraja ~ Head, Foundation Studies
Medicine
- About
-
- Teaching
-
- MD1010: Introduction to Integrated Medical Studies Part 1 of 2 (Level 1; CNS & TSV)
- MD2011: Integrated Human System Pathophysiology Part 1 of 2 (Level 2; TSV)
- MD2012: Integrated Human System Pathophysiology Part 2 of 2 (Level 2; TSV)
- MD3000: Selective Study (Level 3; TSV)
- MD3011: Introduction to Clinical Healthcare Part 1 of 2 (Level 3; TSV)
- MD3012: Introduction to Clinical Healthcare Part 2 of 2 (Level 3; TSV)
- MD6010: Advanced Clinical Medicine Part 1 of 3 (Level 6; TSV)
- MD6020: Advanced Clinical Medicine Part 2 of 3 (Level 6; TSV)
- MD6030: Advanced Clinical Medicine Part 3 of 3 (Level 6; TSV)
- Interests
-
- Research
-
- Rheumatoid arthritis; Bioflavonoids and collagen-induced arthritis; Anti-rheumatoid arthritic activity of flavonoids; Anti-rheumatoid arthritic activity of hookworm proteins; Diabetes; Diabetic foot ulcer; Growth factors in diabetic foot ulcer
- Immunotherapy for Rheumatoid Arthritis
- Bioflavonoids and inflammatory pathways in Rheumatoid Arthritis
- Neuroprotective effects of palm phytonutrients in Parkinson’s disease (Primary Advisor -International Medical University, Kuala Lumpur, Malaysia)
- Neuroprotective effects of Vitamin E on oxidative stress-induced dopaminergic neuronal dysfunction in Parkinson’s disease (Secondary Advisor -International Medical University, Kuala Lumpur, Malaysia)
- Biomarkers of diabetic foot ulcer
- Teaching
-
- Physiology, Pathophysiology, Endocrinology, Neurophysiology, Hematology and Renal Physiology
- Learning styles and approaches of undergraduate medical students
- Evaluating the impact of an integrated blended e-learning program on learning delivery and enhancement in medical education
- Evaluating the impact of mobile integrated learning resources on medical student learning outcomes
- Experience
-
- 2018 to present - Associate Professor, James Cook University (Australia)
- 2011 to 2020 - Adjunct Associate Professor, International Medical University (Kuala Lumpur, Malaysia)
- 2011 to 2017 - Senior Lecturer, James Cook University (Australia)
- 2009 to 2011 - Associate Professor, International Medical University (Kuala Lumpur, Malaysia)
- 2004 to 2009 - Senior Lecturer, International Medical University (Kuala Lumpur, Malaysia)
- 2002 to 2004 - Associate Professor, Manipal University (Manipal, India)
- 1998 to 2002 - Assistant Professor, Manipal University (Manipal, India)
- 1989 to 1998 - Lecturer, Manipal University (Manipal, India)
- Research Disciplines
- Socio-Economic Objectives
Nagaraja Haleagrahara is the Associate Professor at the College of Medicine and Dentistry. His Research Portfolio interests are diverse including oxidative stress; antioxidants; animal models of human diseases; neurodegeneration; diabetes mellitus and rheumatoid arthritis. Currently, his research team at JCU utilize a multidisciplinary approach to research novel anti-inflammatory therapies for rheumatoid arthritis. Nagaraja has managed several peer-reviewed research grants from research institutions in Malaysia and Australia in the past fifteen years. Nagaraja proves extensive experience teaching physiology and pathophysiology in the tertiary setting since 1989. He has taught Physiology across a range of undergraduate, and postgraduate subjects and content areas. Passionate about supporting students at all levels to become intensely engaged in learning as a lifelong endeavour he aims to focus beyond final grades. Nagaraja has been consistently active in Tertiary Education Research with a keen interest in medical education focusing on problem-based learning, blended learning, and learning technologies.
- Honours
-
- Fellowships
-
- 2020 - $ 4250 - CMT Researcher Grant, JCU
- 2018 - $ 1,416 - JCU - Biomedicine Staff Research Enhancement Scheme
- 2018 - Fellow, Royal Society of Biology (UK)
- 2017 - $3, 000 - JCU Learning and Teaching Blended Learning and Innovation Grant (AI)
- 2017 - $ 3,000 - JCU Learning and Teaching Peer Review of Teaching Grant
- 2017 - $ 50,000 - Malaysian Palm Oil Board (MPOB), Kuala Lumpur, Malaysia (AI)
- 2017 - $ 3,660 - JCU - Biomedicine Staff Research Enhancement Scheme
- 2016 - $ 10,000 - JCU – Bridging the Gap Research Grant
- 2015 - $ 30,000 - Arthritis Australia – National Research Project Grant
- 2014 - $ 30, 600 - JCU Research Infrastructure Block Grant (RIBG) (AI)
- 2013 - $ 12,000 – JCU - Research Infrastructure Block Grant (RIBG) (AI)
- 2013 - $ 15, 000 - JCU – AITHM Funded Faculty Research Grant
- 2012 - $ 6,000 - International Medical University, Kuala Lumpur, Malaysia. Faculty Research Grant (AI)
- 2012 - $ 5,000 – JCU - Faculty Research Grant (AI)
- 2011 - $ 15,000 - International Medical University, Kuala Lumpur, Malaysia. Faculty Research Grant (AI)
- 2011 - $ 15,000 - International Medical University, Kuala Lumpur, Malaysia. Faculty Research Grant
- 2010 - $ 12,000 - International Medical University, Kuala Lumpur, Malaysia. Faculty Research Grant
- 2009 - $ 12,000 - International Medical University, Kuala Lumpur, Malaysia. Faculty Research Grant
- 2009 - $ 15,000 - Ministry of Health (MOH) Research Grant, Malaysia (AI)
- 2008 - $ 15,000 - E-Science Fund, Ministry of Science, Technology and Innovation (MOSTI), Malaysia (AI)
- 2008 - $ 6,000 - International Medical University, Kuala Lumpur, Malaysia. Faculty Research Grant
- 2007 - $ 12,000 - International Medical University, Kuala Lumpur, Malaysia. Faculty Research Grant
- 2006 - $ 6,000 - International Medical University, Kuala Lumpur, Malaysia. Faculty Research Grant
- Memberships
-
- 2017 - Higher Education Research and Development Society of Australasia (HERDSA)
- 2017 - Biomedicine – Discipline Research Committee Member
- 2017 - Nutrition Society of Australia (NSA)
- 2012 - JCU School of Medicine 1 Foundation Studies Committee Member
- 2012 - Australian Physiological Society (AuPS)
- 2012 - JCU School of Medicine-Year 1 Assessment Committee Member
- 2012 - Australian Neuroscience Society (ANS)
- 2011 - JCU School of Medicine-Year 2 Assessment Committee Member
- 2008 - Society for Neuroscience (SFN)
- 2007 - Society for Free Radical Biology and Medicine (SFRBM)
- 2005 - American Physiological Society (APS)
- Other
-
- 2008 - The Society for Free Radical Biology and Medicine (SFRBM) – Annual Meeting Abstract Judge
- Publications
-
These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.
- Journal Articles
-
- Langdon K, Buitrago G, Pickering D, Giacomin P, Loukas A and Haleagrahara N (2022) Na-AIP-1 secreted by human hookworms suppresses collagen-induced arthritis. Inflammopharmacology, 30 (2). pp. 527-535
- Magalingam K, Somanath S, Ramdas P, Nagaraja H and Radhakrishnan A (2022) 6?Hydroxydopamine induces neurodegeneration in terminally differentiated SH?SY5Y neuroblastoma cells via enrichment of the nucleosomal degradation pathway: a global proteomics approach. Journal of Molecular Neuroscience, 72. pp. 1026-1046
- Magalingam K, Somanath S, Nagaraja H, Selvaduray K and Radhakrishnan A (2022) Unravelling the neuroprotective mechanisms of carotenes in differentiated human neural cells: biochemical and proteomic approaches. Food Chemistry: Molecular Sciences, 4.
- Magalingam K, Somanath S, Md S, Nagaraja H, Fu J, Selvaduray K and Radhakrishnan A (2022) Tocotrienols protect differentiated SH-SY5Y human neuroblastoma cells against 6-hydroxydopamine-induced cytotoxicity by ameliorating dopamine biosynthesis and dopamine receptor D2 gene expression. Nutrition Research, 98. pp. 27-40
- Magalingam K, Radhakrishnan A, Somanath S, Md S and Haleagrahara N (2020) Influence of serum concentration in retinoic acid and phorbol ester induced differentiation of SH-SY5Y human neuroblastoma cell line. Molecular Biology Reports, 47. pp. 8775-8788
- Langdon K, Phie J, Thapa C, Biros E, Loukas A and Haleagrahara N (2019) Helminth-based therapies for rheumatoid arthritis: a systematic review and meta-analysis. International Immunopharmacology, 66. pp. 366-372
- Venkatesh S, Rao Y, Nagaraja H, Woolley T, Alele F and Malau-Aduli B (2019) Factors influencing medical students’ experiences and satisfaction with blended integrated e-learning. Medical Principles and Practice, 29 (1).
- Langdon K and Nagaraja H (2018) Regulatory T-cell dynamics with abatacept treatment in rheumatoid arthritis. International Reviews of Immunology, 37 (4). pp. 206-214
- Le Rossignol S, Ketheesan N and Nagaraja H (2018) Redox-sensitive transcription factors play a significant role in the development of rheumatoid arthritis. International Reviews of Immunology, 37 (3). pp. 129-143
- Magalingam K, Radhakrishnan A, Ping N and Haleagrahara N (2018) Current concepts of neurodegenerative mechanisms in Alzheimer's disease. BioMed Research International, 2018.
- Nagaraja H, Hodgson K, Miranda-Hernandez S, Hughes S, Bangra Kulur A and Ketheesan N (2018) Flavonoid quercetin-methotrexate combination inhibits inflammatory mediators and matrix metalloproteinase expression, providing protection to joints in collagen-induced arthritis. Inflammopharmacology, 26 (5). pp. 1219-1232
- Haleagrahara N, Miranda-Hernandez S, Alim M, Hayes L, Bird G and Ketheesan N (2017) Therapeutic effect of quercetin in collagen-induced arthritis. Biomedicine & Pharmacotherapy, 90. pp. 38-46
- More
-
ResearchOnline@JCU stores 50+ research outputs authored by A/Prof Haleagrahara Nagaraja from 2009 onwards.
- Current Funding
-
Current and recent Research Funding to JCU is shown by funding source and project.
Diabetes Australia - General Grant
Extracorporeal Shockwave Therapy for Prevention of Diabetic Foot Ulcer Recurrence: A Pilot Study.
- Indicative Funding
- $69,500 over 1 year
- Summary
- Diabetic foot ulcer (DFU) is a common complication of diabetes with a recurrence of up to 40% within one year after initial healing. The common cause for recurrence of DFUs is impaired perfusion of lower extremities due to diabetes. This study aims to determine whether extracorporeal shockwave therapy (ESWT) can prevent the recurrence of previously healed DFUs since it has been shown that low-energy ESWT can improve microcirculation blood flow of ischemic limbs.
- Investigators
- Usman Malabu, Venkat Vangaveti, Erik Biros, Ramesh Velu, Kunwarjit Sangla and Haleagrahara Nagaraja (College of Medicine & Dentistry)
- Keywords
- Diabetes Mellitus; Extracorporeal Shockwave Therapy; Diabetic Footlu cers; Prevention
- Supervision
-
Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor.
These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.
- Current
-
- The Role of the Transforming Growth Factor Beta (TGF-?) Family in Diabetic Foot Ulcer (DFU) Recovery (Masters , Primary Advisor)
- Collaboration
-
The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.- 5+ collaborations
- 4 collaborations
- 3 collaborations
- 2 collaborations
- 1 collaboration
- Indicates the Tropics (Torrid Zone)
Connect with me
- Phone
- Location
- Advisory Accreditation
- Primary Advisor
- Find me on…
-
My research areas
Similar to me
-
A/Prof Allison CravenHumanities, Arts & Social Sciences
-
Dr Mangalam SankupellayInformation Technology
-
A/Prof Monica JurinAccounting
-
Prof Arusha CoorayAccounting
-
Dr Michael UnderdownCairns Institute