About

Biography

Dr. Phurpa Wangchuk is a Senior Research Fellow at the Australian Institute of Tropical Health and Medicine (AITHM), concurrently serving as a Medical/Biomedicine Lecturer at the College of Public Health, Medical, and Veterinary Sciences (CPHMVS). He is a medicinal chemist and he is a group leader currently leading a dedicated research team to find treatments for inflammatory bowel disease (IBD) and related diseases. Dr. Wangchuk was an NHMRC Peter Doherty Biomedical Fellow (ECF) and a recipient of the Australian Endeavour Award and DANIDA Fellowships. He works closely with the Aboriginal Communities of Queensland in the biodiscovery space. Dr. Wangchuk's multifaceted contributions to academia, research, and professional leadership underscore his dedication to advancing biomedical science and addressing critical healthcare challenges.

Educational achievements: Dr. Wangchuk acquired his:

  • Ph.D. with an ‘Outstanding Thesis’ from the University of Wollongong (UOW), Australia.
  • M.Phil. (Medicinal Chemistry) from UOW.
  • Post Graduate Diploma in Research Methodology (Clinical Research) with HD from the DBL-Centre for Health Research and Development, Copenhagen University, Denmark.
  • Bachelor of Science (Major in Chemistry, Botany, and Zoology) from the University of Delhi, India with an ‘Overall Academic Excellence Award’.

Grant achievements: He was awarded the following highly competitive grants (Category A) and has led/leading the research projects as Chief Investigator A. In addition, he obtained several other small grants from Far North Hospital Foundation Research Grants (listed under the funding tab):

  • National Health and Medical Research Council (NHMRC) Ideas Grant (CIA, 2024-2028)
  • NHMRC Ideas Grant (CIA, 2020-2024)
  • NHMRC Early Career Peter Doherty Biomedical Fellowship (currently called NHMRC Investigator Grant for Emerging Leadership Fellow, 2015-2019).
  • Australian Endeavour Fellowship Award (2010-2014).
  • Danish DANIDA Research Fellowship (2006).
  • Royal Government of Bhutan M.Sc. Scholarship (2002-2004).

Awards and prizes: He was awarded:

  • University level - 2 consecutive conference awards for best Ph.D oral presentation organized by the University of Wollongong, Australia
  • State level: 2 consecutive Royal Australian Chemical Institute (RACI) conference prizes for best student talk and poster presentation organized by RACI, New South Wales, Australia
  • International level: 2 international conference prizes/awards for best communication (in Spain organized by Phytochemical Society of Europe) and best poster presentation (in Greece organized by Molecular Parasitology Society).

Research program: Dr. Wangchuk developed a research program called 'Nature-inspired therapeutics for inflammatory bowel disease'. His drug discovery research at AITHM and CPHMVS focuses on discovering novel anti-inflammatory, antiparasitic, antimicrobial, antidiabetic, and antimalarial drug leads from natural sources such as medicinal plants, climate-affected plants, insect fungi, parasitic helminths, and other tropical flora and fauna. His research projects resulted in the discovery of 10 novel molecules, 18 drug lead compounds, and 3 patent/provisional patents on the novel antimalarial and anti-inflammatory drug leads.

Metabolomics platform: Dr. Wangchuk established a GCMS and LCMS metabolomics platform for helminth's small molecules research at JCU, which is the first of its kind in the field of parasitology. He identified biomarkers including polar metabolites and novel lipids with potential applications in developing diagnostics and therapeutics.

Research group: Group leader at AITHM/CPHMVS and he is leading a group of eight researchers including:

  • Postdoc - Dr. Matthew Perry
  • Postdoc - Dr. Karma Yeshi
  • Adjunct Postdoc - Dr. Edita Ritjemeryte
  • Ph.D. student - Mr. Tenzin Jamtsho
  • Ph.D. student - Mr. Felix Wambua
  • Ph.D. student - Mrs. Handa Muliasari
  • M.Phil student - Mr. Gerry Turpin
  • M.Phil student - Mr. Andres Alverez
  • M.Phil student - Mr. Ngawang Gempo 
  • Visiting student from Germany- Mara Curic.

Cosupervisor to:

  • Ph.D student - Mrs. Jessica Watt (JCU)
  • P.hD student - Ms. Preetha Ebenezer (Queensland University of Technology).

Potential research candidates interested in undertaking a Ph.D. or Masters project/Honours should contact Dr. Wangchuk to discuss potential projects. Funding is available through:

https://www.jcu.edu.au/graduate-research-school/hdr-candidates/postgraduate-research-scholarships.

Available research techniques and technologies: His research laboratory uses innovative and integrated techniques of:

  • Natural products chemistry, metabolomics, drug development, ethnobotany, molecular biology, parasitology, and immunology.
  • Advanced analytical technologies including HPLC, MALDI-MS, GCMS, LCMS, and NMR for isolation, structure elucidation, and identification of novel compounds.
  • In vitro (PBMC), in vivo (animal models), and ex vivo (for parasites) experimental models

Past and present professional leadership roles: Prior to his appointment at JCU, he worked in Bhutan in various capacities as a Chemist, Product Manager, and Head of the Research and Development Section of Manjong Sorig Pharmaceuticals. As a Head of R&D, he led a team comprising ethnobotanist, pharmacognosist, traditional physicians, and external technical consultants from Europe, Japan, India, and Thailand. He implemented four World Health Organisation grants and was an executive team member involved in deciding and executing the million Euros European Union Medicinal Plants Project in Bhutan. 

He currently serves in the following professional bodies/capacities as a/an:

  • Scientific reviewer for more than 33 reputed international journal papers
  • Assessor for books and grant proposals
  • Examiner for the HDR thesis (National and International)
  • Active member of the NHMRC Ideas grant review panel
  • Editor, and editorial board member of four reputed international journals. 

Teaching/Supervising/Marking:

  • MD1010 - Introduction to Integrated Medical Studies Part 1 of 2 (Medical Biochemistry).
  • MD1010 - Introduction to Integrated Medical Studies Part 2 of 2 (Genetics and Health).
  • TV3002 Research Proposals - Veterinary Sciences Year 3.
  • NRS-MBBS 6 Research Activity Task- MBBS Year 6
  • DS40101 Research Task - Dentistry Year 4.
Teaching
  • MD1020: Introduction to Integrated Medical Studies Part 2 of 2 (Level 1; CNS & TSV)
Interests
Research
  • Parasitology-worms and their anti-inflammatory compounds
  • Anti-inflammatory and anthelmintic alkaloids/flavonoids
  • Phytochemicals and pharmacology of medicinal and parasitic plants
  • Insect-fungi and their bioactive secondary metabolites
  • North Queensland Natural Products, their chemistry and therapeutic applications
  • Metabolomics and biomarkers of natural compounds and diseases
Experience
  • 2020 to 2024 - Topic Editor for the international journal "Plants", Journal publisher (Switzerland)
  • 2018 to 2024 - Guest Editor for the international journal 'Molecules', Journal publisher (Switzerland)
  • 2015 to 2019 - NHMRC ECR Fellow, James Cook University (Cairns)
  • 2014 - Research Officer, James Cook University (Cairns, Australia)
  • 2010 to 2014 - PhD Research Candidate, University of Wollongong (NSW, Australia)
  • 2008 to 2009 - Editor of Quarterly Morbidity and Activity Report, Ministry of Health (Bhutan)
  • 2008 to 2009 - Editor of Manjong Sorig Journal, Ministry of Health (Bhutan)
  • 2007 to 2009 - Product Manager, Manjong Sorig Pharmaceuticals, Kawajangsa, Thimphu District, Bhutan (Thimphu, Bhutan)
  • 2006 to 2009 - Head of R&D, Manjong Sorig Pharmaceuticals (Thmphu, Bhutan)
  • 2006 to 2009 - Executive Team (representing R&D section) of the European Union Project-II, Manjong Sorig Pharmaceuticals, Kawajangsa, Thimphu District, Bhutan (Thimphu, Bhutan)
  • 2006 to 2007 - Secretary of Research and Development of Bhutan, MSP/MoH (Bhutan)
  • 2006 - DANIDA Research Fellowship, DBL-Centre for Health Research and Development, University of Copenhagen (Denmark)
  • 2004 to 2006 - Chemist, Pharmaceutical and Research Unit (Thmphu, Bhutan)
  • 2002 to 2004 - M.Sc. Research Candidate, University of Wollongong (NSW, Australia)
  • 1999 to 2002 - Research Officer, Pharmaceutical and Research Unit (Thmphu, Bhutan)
Socio-Economic Objectives
Honours
Awards
  • 2023 to 2026 - HDR PhD Scholarship to T. Jamtsho (~AUD $266,400)
  • 2022 to 2024 - HDR M.Phil Scholarship to A. Alverez (~AUD $148,000)
  • 2023 - JCU HDR Supervisor of the Year 2023.
  • 2020 to 2023 - HDR PhD Scholarship to K. Kaposi (~AUD $190,800)
  • 2019 to 2023 - HDR PhD Scholarship to K. Yeshi (~AUD $255,600)
  • 2022 - Invited Plenary Speaker for the International Conference on Medicinal Plants, Jember University, Indonesia.
  • 2022 - Invited Guest Lecture at Yangchenphug and Jigme Sherubling Higher Secondary Schools, Bhutan
  • 2022 - Invited Talk at Queensland Pharmacy Students' Association Research Night
  • 2022 - Invited Guest Speaker for MEd Biology and STEM Programme, Samtse College of Education, Royal University of Bhutan.
  • 2021 - Invited Guest Speaker at Cairns Marlin Coast Probus.
  • 2021 - Invited Guest Lecture - Mendrelgang Secondary School, Bhutan
  • 2020 - Inaugural Talk - Drukrig Network of Bhutan Scholars.
  • 2020 - Invited Guest Lecture - Jember University, Indonesia
  • 2019 - Invited speaker to The Second Annual Canadian Metabolomics Conference
  • 2018 - Special Address/Talk invitation -fully funded by the international conference on JIGNASA 2018 International conference, India
  • 2018 - Invited Speaker to the International conference in Beijing (fully funded by the conference organiser)
  • 2018 - Invited Keynote Speaker -fully funded by the international conference on medicine and health sciences, Indonesia
  • 2017 - Conference travel grant for organising and chairing a biodiscovery panel at ICTAM IX, Germany
  • 2017 - Invited speaker at International Conference on Medical and Health Sciences, Bhutan
  • 2017 - Full conference travel award as an 'Invited Speaker' at Harvard Conference on Health-Body-Mind
  • 2016 to 2017 - Australian Institute of Tropical Health and Medicine Capacity Building Grant
  • 2016 - Best Poster Presentation Award - awarded in the International Conference on 'Molecular and Cellular Biology of Helminth Parasites X' held at Hydra (4-9 September 2016).
  • 2015 - "Invited speaker" Travel Award -International conference on 'Utilising Sub-Himalayan Biological Resources (fully funded by the conference organiser-Dibrugarh University, India)
  • 2014 - Examiners' special commendations for outstanding PhD thesis
  • 2009 to 2014 - Australian Endeavour Post Graduate Award
  • 2013 - ICTAM VIII Congress Award for attending the conference held every after 4 years
  • 2013 - KIOM-South Korea keynote speaker full funding award for the International Symposium on Value and Folk Remedy as Traditional Knowledge
  • 2013 - Bhutan Royal Civil Service Award for dedicated service (10 years) to the nation and the public
  • 2012 - Phytochemical Society of Europe's Best Congress Communication Award
  • 2012 - UOW Faculty of Science post graduate conference funding award
  • 2011 - Royal Australian Chemical Institute (RACI) 2011 Best Oral Presentation Runner up Award
  • 2011 - UOW 2011 Highly Commended PhD Presentation Award
  • 2010 - Royal Australian Chemical Institute (RACI) 2010 Best PhD Meritorious Poster Presentation Award
  • 2010 - BlueScope Steel Research Innovation Awards 2010
  • 2008 - RCSC meritorious promotion
  • 2007 - International Centre for Environmental Health and Toxicology Training Award, Thailand
  • 2000 - United Nations Industrial Development Organization Training Workshop Award
  • 1998 - Graduate Academic Excellence Award
Fellowships
  • 2015 to 2019 - National Health and Medical Research Council ECR Grant
  • 2010 to 2014 - Australian Endeavour Award-PhD
  • 2006 - DANIDA Fellowship for Post Graduate Diploma in Social/Clinical Research Methodology, Denmark.
  • 2002 to 2004 - Royal Government of Bhutan M.Sc. Scholarship
Memberships
  • 2014 to 2026 - Editorial Board of the Journal of Biologically Active Products from Nature
  • 2008 to 2026 - Organiser and Editor of the Manjong Sorig Journal
  • 2020 to 2024 - 'Subject/Topic Editor' for an international journal 'Plants' (Impact Factor 2.8)
  • 2020 to 2024 - Guest Editor for an international journal 'Molecules' (Impact Factor 3.2)
  • 2016 to 2024 - Australia & New Zealand Society for Magnetic Resonance (ANZMAG )
  • 2013 to 2024 - Council Member of The International Association for the Study of Traditional Asian Medicine (Germany)
  • 2012 to 2016 - Member of the Phytochemical Society of Europe
  • 2014 - The Australian Society for Parasitology
  • 2010 to 2014 - Chemical Society of University of Wollongong
  • 2008 to 2009 - Member of the National Scientific Review Committee of Bhutan
  • 2008 to 2009 - Editorial Board of the Bhutan Ministry of Health Quarterly and Morbidity Activity Report
  • 2005 to 2009 - Research Core Group and Quality Assurance Team of Manjong Sorig Pharmaceuticals
  • 2007 to 2008 - Non-Wood Forest Products Task Force
  • 2007 - Ethnobotany
  • 2007 - Biodiversity Action Plan Development Technical Committee Member
Other
  • 2024 - Invited Guest Lecture to 3rd Year Medical Students on IBD and therapeutics
  • 2021 - Invited Reviewer for Food Reviews International
  • 2020 - Invited Reviewer for Metabolomics
  • 2020 - Invited Reviewer of Phytotherapy Research
  • 2020 - Invited Reviewer for Communication Biology (Nature GP)
  • 2020 - Invited Reviewer for Phytochemistry
  • 2019 - PhD thesis Examiner for Macquarie University
  • 2018 - Invited Reviewer of the 'International Wound Journal'
  • 2018 - Invited reviewer -Acta Parasitologica
  • 2018 - Invited Reviewer for the BMC Infectious Diseases
  • 2024 - Invited Special Guest Seminar Lecture at Department of Chemistry, Faculty of Science, Mahasarakham University (MSU), Thailand
  • 2024 - Invited talk for the medicinal chemistry class, Macquarie University, NSW, Australia
  • 2024 - Invited Guest Speaker at the special guest seminar organised by Department of Chemistry, Faculty of Science, Mahasarakham University (MSU), Thailand
  • 2022 - Plenary speaker at the International Conference in Indonesia.
  • 2022 - Invited Plenary Speaker at the International Conference in Indonesia.
  • 2021 - Invited Reviewer for 'Cell Biology and Toxicology'
  • 2021 - Invited Reviewer for 'Horticulture Research'-Nature
  • 2021 - Invited Reviewer for 'Communications Biology': https://mts-spd.nature.com/apps/spd.plex?form_type=display_person_manuscripts&mod_p_id=73825&mod_j_id=153.
  • 2020 - M.Sc. Thesis Examiner for Macquarie University
  • 2016 to 2020 - Invited Reviewer of the 'Journal of Ethnopharmacology' Elsevier Impact factor-3.11
  • 2016 to 2020 - Reviewed paper for Molecules
  • 2019 - Invited Reviewer for the 'Bioorganic Chemistry'
  • 2019 - Invited Reviewer of the PLOS Neglected Tropical Diseases
  • 2016 to 2019 - Reviewed paper for International Journal of Molecular Sciences
  • 2016 to 2019 - Reviewed paper for Phytochemistry Letters
  • 2015 to 2019 - Invited Reviewer of the Pharmaceutical Biology
  • 2015 to 2019 - Invited reviewer for the Journal of Biologically Active Products from Nature
  • 2018 - Invited Reviewer of the 'Nutrients'
  • 2018 - Invited Reviewer of the Toxins
  • 2018 - Invited Reviewer of the 'Digestive Diseases and Sciences'
  • 2013 to 2017 - Reviewer for a journal paper-Natural Products Communication
  • 2016 - Reviewed paper for BMC Immunology
  • 2016 - Reviewed paper for International Journal of Parasitology
  • 2015 - Invited Reviewer of the 'Scientific Reports'-Nature Publishing Group.
  • 2015 - Invited Reviewer of the 'BMC Complementary and Alternative Medicine'
  • 2015 - Invited Reviewer of the paper submitted to the BMC Research Notes.
  • 2015 - Invited reviewer for Journal of Ethnobiology and Ethnomedicine
  • 2015 - Invited Reviewer for Ethnobotany Research & Applications
  • 2015 - Invited Reviewer of the BMC Pharmacology and Toxicology
  • 2015 - Invited Reviewer for the Journal of Pharmaceutical and Biomedical Analysis
  • 2015 - Invited Reviewer for the Natural Products Research
  • 2015 - Invited Reviewer of the 'BMC Ecology'
  • 2012 - Guest Reviewer of the Acta Pharmaceutica Sinica B
Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles
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ResearchOnline@JCU stores 97+ research outputs authored by Dr Phurpa Wangchuk from 2007 onwards.

Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

Far North Queensland Hospital Foundation - Research Grant

Evaluation of cytotoxicity, antioxidant and anti-diabetic properties of FNQ bush food

Indicative Funding
$5,000 over 1 year
Summary
Native foods in Australia have a rich history and there is a growing demand for bush foods. The Far North Queensland (FNQ) is considered a hotspot for a wide range of bush foods and yet its commercial production remains small. This study will evaluate the antioxidant, cytotoxicity, and anti-diabetic properties of bushfoods used by the FNQ Mbabaram Aboriginal community. While the data from cytotoxicity and antioxidant screening will help the community in developing unique and safe FNQ bush food products, the antidiabetic data will help us in identifying foods that could be used as i) healthy food substitutes in the restaurant menus, and ii) intervention foods for diabetic patients.
Investigators
Pornphimon Meesakul, Phurpa Wangchuk and Gerald Turpin (Australian Institute of Tropical Health & Medicine and Australian Tropical Herbarium)
Keywords
Bush food; Antioxidant; Natural products; Cytotoxicity; Anti-diabetic

Far North Queensland Hospital Foundation - Research Grant

Biodiscovery from Wet Tropics' native plants

Indicative Funding
$5,000 over 2 years
Summary
Inflammatory bowel disease (IBD) affects 1 in 250 Australians including the people living in the FNQ region. It cost Australians a total of $3.18 billion per annum. Given that it has no cure and the disease prevalence and its associated cost are expected to increase sharply, there is an urgent need for new drugs. Inspired by the Wet Tropics' biodiversity of Far North Queensland (FNQ), the proposed project envisions discovering novel anti-inflammatory drug leads for IBD from selected climate-affected native plants using cutting-edge drug discovery techniques and technologies. The aims are : ? Determine the metabolomes of the anti-inflammatory extracts of five native mountaintop plants using mass spectrometry techniques. ? Isolate anti-inflammatory molecules from Uromyrtus metrosideros extract using chromatographic techniques.
Investigators
Phurpa Wangchuk and Karma Yeshi (Australian Institute of Tropical Health & Medicine)
Keywords
Wet Tropics; Biodiscovery; Inflammatory Bowel Disease; Anti-inflammatory drug lead; Natural Products; Climate change

National Health & Medical Research Council - Ideas Grants

Discovering novel drug lead molecules for inflammatory bowel disease from Australian Aboriginal tropical medicinal plants

Indicative Funding
$1,209,524 over 5 years
Summary
Inflammatory Bowel Disease is a debilitating disease, which has no cure. It costs the Australian Health System billions of dollars in hospitalisation, management and lost productivity, thereby precipitating the need for novel drugs. Building on my extensive preliminary data, we aim to discover novel drug leads from Aboriginal medicinal plants, which are currently used for treating inflammatory conditions by the Mbabaram community of the Atherton Tablelands.
Investigators
Phurpa Wangchuk, Roland Ruscher, Joanne Jamie, Stephen Pyne, Darren Crayn and Gerald Turpin (Australian Institute of Tropical Health & Medicine, Macquarie University, University of Wollongong, College of Science & Engineering and Australian Tropical Herbarium)
Keywords
Aboriginal medicinal plants; Anti-inflammatory activities; Inflammatory Bowel Disease; Biologically active molecules; New drug leads; Metabolomics

Far North Queensland Hospital Foundation - Research Grant

Preclinical evaluation of novel drug lead compounds discovered from Wet Tropics plant

Indicative Funding
$50,000 over 1 year
Summary
Inflammatory bowel disease (IBD) affects 1 in 250 Australians including the people living in Far North Queensland (FNQ). There is no cure for this debilitating disease. Inspired by the Wet Tropics, we have isolated two compounds that demonstrated strong in vitro anti-inflammatory activity. A provisional patent has been approved for these two compounds. To further develop them into the marketable drug lead candidates, this proposed project will endeavor to achieve preclinical evaluation of these two novel compounds using the two commonly used animal models of IBD- Trinitrobenzenesulfonic acid (TNBS) and T cell transfer models of colitis.
Investigators
Phurpa Wangchuk, Karma Yeshi and Paul Giacomin (Australian Institute of Tropical Health & Medicine)
Keywords
Wet Tropics; Biodiscovery; Inflammatory Bowel Disease; Anti-inflammatory drug lead; Natural products; Drug leads

Far North Queensland Hospital Foundation - Research Grant

Exploring the mosquito repellent and larvicidal activities of essential oils against Aedes aegypti

Indicative Funding
$5,000 over 1 year
Summary
To explore the mosquito repellent and larvicidal activities of essential oils (EOs) derived from native plants of wet tropics. Mosquito repellent and larvicidal activities of essential oil (EO) or a combination of EOs will be assessed against Aedes aegypti (primary dengue vector) in the laboratory following World Health Organisation protocols. The repellent and larvicidal activities will be compared with a commercially available mosquito repellent N,N-diethyl-meta-toluamide (20% in ethanol), and permethrin, respectively. The study outcome will ultimately lead to the development of better and more effective mosquito-repellent to prevent bittings and, thus, reduce the dengue burden in Far North Queensland.
Investigators
Karma Yeshi, Boni Sebayang and Phurpa Wangchuk (Australian Institute of Tropical Health & Medicine)

Far North Queensland Hospital Foundation - Research Grant

Documentation and evaluation of Aboriginal medicinal plants for anti-inflammatory agents

Indicative Funding
$5,000 over 1 year
Summary
Aboriginal people in Australia, especially in remote areas, have a vast knowledge of medicinal plants and bush food (Packer et al., 2012) that have supported their sustenance and protected them against different ailments for thousands of years. In Far North Queensland (FNQ), there are more than 18 Aboriginal communities and their customary food and medical knowledge differ from other parts of Australia. Their knowledge is shaped by their rich tropical forests that are home to range of medicinal plants and bush tucker. It is believed that these plants and bush food keep some remote Aboriginal people healthy especially protected against Inflammatory Bowel Disease (IBD). The prevalence of IBD in Indigenous Australians in the Northern Territory is almost 8-37-times less than the non-indigenous population (Leach et al., 2014; Iyngkaran, 2015). Although genetic and other factors cannot be ruled out, diet, which plays a pivotal role in shaping the architecture and functionality of resident microbes in the gut (Zmora et al., 2019), may be responsible for this health outcome. Indeed, some Indigenous populations are known to possess unique microbiota compared to non-indigenous population (Iyngkaran, 2015) and we hypothesize that this could be due to inclusion of medicinal plants and bush food in their diet. Unfortunately, since younger generation are not interested to learn the Aboriginal medicinal plants and bush food knowledge, the rich customary knowledge is dying with the community elders. There is urgent need to document the surviving customary food and medical knowledge of some remote Indigenous communities before they are lost forever, which has both cultural and health ramifications in near future. Therefore, this study proposes to document and study the largely untapped pharmacopoeia of Mbabaram Aboriginal people in Atherton and discover viable medicinal plant candidates for anti-inflammatory screening.
Investigators
Phurpa Wangchuk and Gerald Paul Turpin (Australian Institute of Tropical Health & Medicine)
Keywords
Aboriginal Medicine; Rainforest plants; Biodiscovery; Medicinal Plants; Inflammatory Bowel Disease; Traditional Knowledge

Far North Queensland Hospital Foundation - Research Grant

Preclinical evaluation of phytocompounds as novel antimicrobial agents.

Indicative Funding
$5,000 over 2 years
Summary
Through previous work funded by a FNQ Hospital Foundation Grant (JCU-QLD-838341), we have discovered two novel phytocompounds from tropical medicinal plants that show broad-spectrum antimicrobial properties against drug resistant bacterial strains that affect FNQ. To progress the development of these compounds into potential antibiotics, further pre-clinical in vitro and in vivo testing is required.
Investigators
Phurpa Wangchuk and Andreas Kupz in collaboration with Visai Muruganandah (Australian Institute of Tropical Health & Medicine and College of Medicine & Dentistry)
Keywords
Biologically active molecules; Novel drug leads; Antimicrobial agents; Isolation of compounds; Tropical medicinal plants; Wet Tropics
Supervision

Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current
  • Antimicrobial Properties of Molecular Isolates from Tropical Flora and Fauna (PhD , Secondary Advisor/AM)
  • Novel Antioxidant and Antidiabetic Molecules of tropical bush foods/medicines (PhD , Primary Advisor/AM/Adv)
  • Anti-inflammatory Molecules of the selected Aboriginal Plants and Helminths (PhD , Primary Advisor)
  • Tropical plant-derived drug lead molecules for treating liver cancer (PhD , Primary Advisor)
  • Investigating plant-derived antimicrobial molecules as potential antiviral agents in viral infections (Masters , Secondary Advisor)
  • Isolation of Novel Anti-inflammatory Drug lead Molecules from Australian Tropical Medicinal Plants (Masters , Primary Advisor)
  • Ethnobotany and the biological activities of Iningai and Mbabaram Medicinal Plants (Masters , Primary Advisor)
  • Metabolomics studies of selected Wet Tropic plants threatened by climate change. (Masters , Primary Advisor)
Completed
  • Biodiscovery of anti-inflammatory drug lead molecules from Australian wet tropics plants and parasites (2023, PhD , Primary Advisor)
Data

These are the most recent metadata records associated with this researcher. To see a detailed description of all dataset records, visit Research Data Australia.

Collaboration

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.

  • 5+ collaborations
  • 4 collaborations
  • 3 collaborations
  • 2 collaborations
  • 1 collaboration
  • Indicates the Tropics (Torrid Zone)

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