About

Dr. Phurpa Wangchuk is a National Health and Medical Research Council (NHMRC) early career fellowship holder at JCU. He was an Australian Endeavour Award Holder in 2010-2014 and completed his PhD in Natural Products Chemistry with examiners' special commendation for ‘Outstanding Thesis’ from the University of Wollongong, NSW, Australia. His research project on the phytochemical analysis, bioassays and the identification of drug lead compounds from the medicinal plants resulted into numerous awards, research papers and a patent on the novel antimalarial drug lead compound. Currently, his research at Professor Alex Loukas Laboratory involve the metabolomics, biodiscovery and molecular characterisation of the anti-inflammatory and anthelmintic small molecules from worms, medicinal plants and entomopathogenic fungi using HPLC, MALDI-MS, GCMS, NMR, and the in vitroin vivo and ex vivo experimental models.  

Dr. Phurpa Wangchuk obtained his Bachelor of Bioscience from Sherubtse College with an award conferred for ‘Overall Academic Excellence’. He completed his M.Sc. (Medicinal Chemistry) by Research from the University of Wollongong and obtained the Post Graduate Diploma in Research Methodology (Clinical Research) from the DBL-Centre for Health Research and Development, Faculty of Life Sciences, Copenhagen University, Denmark under DANIDA fellowship.

Prior to his appointment at JCU, he worked for 12 years in Bhutan as a Research Officer, Chemist, Product Manager and as a Head of the Research and Development Section of the Manjong Sorig Pharmaceuticals. He also did laboratory demonstrations to the first year chemistry students while at the University of Wollongong. He has thus far published more than 23 first authored journal papers, 2 books, 4 conference proceedings, 1 plant monograph, and is an active member, reviewer and editorial boards of national and international journals. 

Interests
Research
  • Parasitology-worms and their anti-inflammatory compounds
  • Anti-inflammatory and anthelmintic alkaloids/flavonoids
  • Phytochemicals and pharmacology of medicinal and parasitic plants
  • Insect-fungi and their bioactive secondary metabolites
  • North Queensland Natural Products, their chemistry and therapeutic applications
Experience
  • 2015 to 2018 - NHMRC ECR Fellow, James Cook University (Cairns)
  • 2014 - Research Officer, James Cook University (Cairns, Australia)
  • 2010 to 2014 - PhD Research Candidate, University of Wollongong (NSW, Australia)
  • 2008 to 2009 - Editor of Manjong Sorig Journal, Ministry of Health (Bhutan)
  • 2008 to 2009 - Editor of Quarterly Morbidity and Activity Report, Ministry of Health (Bhutan)
  • 2006 to 2009 - Head of R&D, Manjong Sorig Pharmaceuticals (Thmphu, Bhutan)
  • 2006 to 2007 - Secretary of Traditional Medicine Research and Development of Bhutan, Institute of Traditional Medicine Services (Bhutan)
  • 2006 - DANIDA Research Fellowship, DBL-Centre for Health Research and Development, University of Copenhagen (Denmark)
  • 2004 to 2006 - Chemist, Pharmaceutical and Research Unit (Thmphu, Bhutan)
  • 2002 to 2004 - M.Sc. Research Candidate, University of Wollongong (NSW, Australia)
  • 1999 to 2002 - Research Officer, Pharmaceutical and Research Unit (Thmphu, Bhutan)
Socio-Economic Objectives
Honours
Awards
  • 2016 to 2017 - Australian Institute of Tropical Health and Medicine Capacity Building Grant
  • 2016 - Best Poster Presentation Award - awarded in the International Conference on 'Molecular and Cellular Biology of Helminth Parasites X' held at Hydra (4-9 September 2016).
  • 2015 - Invited speaker Dibrugarh travel funding
  • 2014 - Examiners' special commendations for outstanding PhD thesis
  • 2009 to 2014 - Australian Endeavour Post Graduate Award
  • 2013 - KIOM-South Korea keynote speaker full funding award for the International Symposium on Value and Folk Remedy as Traditional Knowledge
  • 2013 - Bhutan Royal Civil Service Award for dedicated service (10 years) to the nation and the public
  • 2013 - ICTAM VIII Congress Award for attending the conference held every after 4 years
  • 2012 - Phytochemical Society of Europe's Best Congress Communication Award
  • 2012 - UOW Faculty of Science post graduate conference funding award
  • 2011 - UOW 2011 Highly Commended PhD Presentation Award
  • 2011 - Royal Australian Chemical Institute (RACI) 2011 Best Oral Presentation Runner up Award
  • 2010 - BlueScope Steel Research Innovation Awards 2010
  • 2010 - Royal Australian Chemical Institute (RACI) 2010 Best PhD Meritorious Poster Presentation Award
  • 2008 - RCSC meritorious promotion
  • 2007 - International Centre for Environmental Health and Toxicology Training Award, Thailand
  • 2000 - United Nations Industrial Development Organization Training Workshop Award
  • 1998 - Graduate Academic Excellence Award
Fellowships
  • 2015 to 2018 - National Health and Medical Research Council ECR Grant
  • 2010 to 2014 - Australian Endeavour Award-PhD
  • 2006 - DANIDA Fellowship
  • 2002 to 2004 - Royal Government of Bhutan M.Sc. Scholarship
Memberships
  • 2014 - The Australian Society for Parasitology
  • 2014 - Editorial Board of the Journal of Biologically Active Products from Nature
  • 2013 to 2014 - Council Member of The International Association for the Study of Traditional Asian Medicine
  • 2012 to 2014 - Member of the Phytochemical Society of Europe
  • 2010 to 2014 - Chemical Society of University of Wollongong
  • 2008 to 2009 - Editorial Board of the Bhutan Ministry of Health Quarterly and Morbidity Activity Report
  • 2008 to 2009 - Member of the National Scientific Review Committee of Bhutan
  • 2008 to 2009 - Organiser and Editor of the Manjong Sorig Journal
  • 2005 to 2009 - Research Core Group and Quality Assurance Team of Manjong Sorig Pharmaceuticals
  • 2007 to 2008 - Non-Wood Forest Products Task Force
  • 2007 - Biodiversity Action Plan Development Technical Committee Member
  • 2007 - Ethnobotany
Other
  • 2016 - Reviewed paper for International Journal of Molecular Sciences-IF=3.25
  • 2016 - Reviewed paper for BMC Immunology-IF=2.16
  • 2016 - Invited Reviewer of the 'Journal of Ethnopharmacology' Elsevier Impact factor-2.99
  • 2016 - Reviewed paper for Molecules-IF = 2.45
  • 2016 - Reviewed paper for Phytochemistry Letters-IF=1.35
  • 2016 - Reviewed paper for International Journal of Parasitology-IF=4.2
  • 2015 - Invited Reviewer of the Journal of Pharmaceutical and Biomedical Analysis-Impact factor = 2.97
  • 2015 - Invited Reviewer of the 'BMC Ecology'-2014 Impact factor-2.36
  • 2015 - Invited Reviewer of the paper submitted to the Ethnobotany Research & Applications
  • 2015 - Invited Reviewer of the Pharmaceutical Biology-impact factor = 1.24
  • 2015 - Invited reviewer for Journal of Ethnobiology and Ethnomedicine-Impact factor = 2.0
  • 2015 - Invited Reviewer for the Natural Products Research-Impact factor = 0.92
  • 2015 - Invited Reviewer of the BMC Pharmacology and Toxicology-Impact factor = 1.84
  • 2015 - Invited Reviewer of the 'Scientific Reports'-Nature Publishing Group-2014 Impact factor-5.58.
  • 2015 - Invited reviewer for the Journal of Biologically Active Products from Nature
  • 2015 - Invited Reviewer of the paper submitted to the BMC Research Notes.
  • 2015 - Reviewer for a journal paper-Natural Products Communication Impact factor =0.90
  • 2015 - Invited Reviewer of the 'BMC Complementary and Alternative Medicine'- 2015 Impact factor-2.02
  • 2013 - Invited Reviewer of the Natural Product Communications
  • 2012 - Guest Reviewer of the Acta Pharmaceutica Sinica B
Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles
Book Chapters
  • Wangchuk P, Gyeltshen T and Tobgay T (2016) Bhutanese Traditional Medical Education. In: Education in Bhutan: culture, schooling, and gross national happiness. Education in the Asia-Pacific Region: issues, concerns and prospects, 36. Springer, pp. 91-108
More

ResearchOnline@JCU stores 34+ research outputs authored by Dr Phurpa Wangchuk from 2007 onwards.

Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

NHMRC - Early Career Fellowship

Isolation and pre-clinical evaluation of small molecule anti-inflammatory compounds from hookworms

Indicative Funding
$309,436 over 4 years
Summary
Taking cues from millennia of host-parasite co evolution, my research envisions harnessing the unique ability of hookworm to modulate inflammation and would determine the therapeutic potential of the low molecular weight cultured excretory/secretory (<10 kDa) and the somatic extracts of adult hookworms. It aims on: (1) Isolating, structure elucidating and identifying small drug lead compounds; (2) Derivatizing these bioactive molecules; and (3) Evaluating the anti-inflammatory activity of rude extracts and their compounds using in vivo and ex vivo experimental mouse models. This study would lead to novel anti-inflammatory drug discovery that has implications to the Australian patients with inflammatory bowel diseases.
Investigators
Phurpa Wangchuk (Australian Institute of Tropical Health & Medicine)
Keywords
Anti-inflammatory; Drug Discovery; Hookworm; Excretory/secretory Proteins; Inflammatory Bowel Disease; small molecule
Supervision

Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current
  • Low Molecular Weight Proteins Produced by Hookworms (Ancylostoma caninum) and Their Use as Anti-Inflammatory Agents. (PhD , Secondary Advisor)
Collaboration

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.

  • 5+ collaborations
  • 4 collaborations
  • 3 collaborations
  • 2 collaborations
  • 1 collaboration
  • Indicates the Tropics (Torrid Zone)

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