
Prof Alan Nimmo ~ JCU Professor
Academy Division
- About
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- Research Disciplines
- Socio-Economic Objectives
- Publications
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These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.
- Journal Articles
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- Ronca S, Gunter S, Kairis R, Lino A, Romero J, Pautler R, Nimmo A and Murray K (2022) A Potential Role for Substance P in West Nile Virus Neuropathogenesis. Viruses, 14 (9).
- Akl S, Ranatunga M, Long S, Jennings E and Nimmo A (2021) A systematic review investigating patient knowledge and awareness on the association between oral health and their systemic condition. BMC Public Health, 21.
- Currell S, Blackmore Grant P, Esterman A and Nimmo A (2021) The clinical management of orthodontically-induced external root resorption: a questionnaire survey. American Journal of Orthodontics and Dentofacial Orthopedics, 160 (3). pp. 385-391
- Martin E, Jennings E, Lee A and Nimmo A (2021) Articaine in dentistry: an overview of the evidence and meta-analysis of the latest randomised controlled trials on articaine safety and efficacy compared to lidocaine for routine dental treatment. British Dental Journal Open, 7.
- Sholapurkar A, Sharma D, Glass B, Miller C, Nimmo A and Jennings E (2021) Professionally delivered local antimicrobials in the treatment of patients with periodontitis— a narrative review. Dentistry Journal, 9 (1).
- Khan A, Goyal A, Somaiya V, Rathesh A, Sathiyamoorthy J, Larkin K, Currell S and Nimmo A (2020) Knowledge of Australian primary education providers towards dental avulsion injuries: a cross-sectional study. Australian Dental Journal, 65 (1). pp. 46-52
- Piontek M, Seymour J, Wong Y, Gilstrom T, Potriquet J, Jennings E, Nimmo A and Miles J (2020) The pathology of Chironex fleckeri venom and known biological mechanisms. Toxicon, 6.
- Currell S, Liaw A, Blackmore Grant P, Esterman A and Nimmo A (2019) Orthodontic mechanotherapies and their influence on external root resorption: a systematic review. American Journal of Orthodontics and Dentofacial Orthopedics, 155 (3). pp. 313-329
- Elhousiny M, Miller K, Ariyawadana A and Nimmo A (2019) Identification of inflammatory mediators associated with metastasis of oral squamous cell carcinoma in experimental and clinical studies: systematic review. Clinical and Experimental Metastasis, 36. pp. 481-492
- Liaw A, Miller C and Nimmo A (2019) Comparing the periodontal tissue response to non‐surgical scaling and root planing alone, adjunctive azithromycin, or adjunctive amoxicillin plus metronidazole in generalized chronic moderate‐to‐severe periodontitis: a preliminary randomized controlled tr. Australian Dental Journal, 64 (2). pp. 145-152
- Lewis K, Harford-Wright E, Vink R, Nimmo A and Ghabriel M (2013) Walker 256 tumour cells increase substance P immunoreactivity locally and modify the properties of the blood-brain barrier during extravasation and brain invasion. Clinical and Experimental Metastasis, 30 (1). pp. 1-12
- Donkin J, Nimmo A, Cernak I, Blumbergs P and Vink R (2009) Substance P is associated with the development of brain edema and functional deficits after traumatic brain injury. Journal of Cerebral Blood Flow & Metabolism, 29 (8). pp. 1388-1398
- More
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ResearchOnline@JCU stores 31+ research outputs authored by Prof Alan Nimmo from 2000 onwards.
- Current Funding
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Current and recent Research Funding to JCU is shown by funding source and project.
Commonwealth Department of Health - Medical Research Future Fund - Cardiovascular Health Mission
The SPRINTS Project: Stroke - Prevention of Reperfusion
- Indicative Funding
- $797,893 over 4 years (administered by University of Adelaide)
- Summary
- Stroke represents a major clinical and social burden, being a leading cause of death, but also adult disability and dementia. The SPRINTS Project represents a novel therapeutic approach to significantly improve patient outcomes following an ischaemic stroke. The project represents a low-risk strategy to deliver a novel therapeutic agent to clinical trial for this area of high medical need. Through direct engagement with our world-leading clinical team, as well as with patient and consumer advocates, we expect the SPRINTS project to improve patient outcomes from acute stroke events, providing direct benefits to Australia and Australians.
- Investigators
- Renee Turner, Henry Ma, Alan Nimmo, Connie Wong, James Bourne, Nicholas Veldhuis, Jonathan Baell, Michelle McIntosh and Daniel Poole (University of Adelaide, Monash Health, Academy and Monash University)
- Keywords
- Ischaemic stroke; Neuroinflammation; Reperfusion iINjury; Blood brain barrier; NK1- Recepter Antagonist; Haemorrhagic transformation
National Health & Medical Research Council - Development Grant
Preventing reperfusion injury in stroke with an acutely dosed NK1R antagonist prodrug
- Indicative Funding
- $20,000 over 2 years (administered by Monash University)
- Summary
- Stroke represents a major clinical and societal burden, being a leading cause of adult disability, dementia, and death. The aim is to develop a novel therapeutic approach to significantly improve patient outcomes following an ischaemic stroke through the development of a novel therapeutic agent that can be delivered in conjunction with current approved reperfusion therapy. The plan involves critical de-risking efforts to deliver a low-risk strategy for progression to clinical trial. The plan focuses on the development of prodrugs of the NK1R antagonist, befetupitant, appropriately soluble for i.v. dosing, and accompanied by preclinical PK-PD data for formal, rapid preclinical development.
- Investigators
- Jonathan Baell, Alan Nimmo, Susan Charman, Connie Wong and Nicholas Veldhuis (Monash University and Academy)
- Keywords
- Stroke; Reperfusion Injury; Tachykinin NK1 receptor; Intravenous formulation; NK1 receptor antagonist; Prodrug development
- Supervision
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Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor.
These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.
- Current
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- Comparison of Efficacy of Local and Systemic Antibiotics in Combination with Scaling and Root Planning in Patients with Moderate to Severe Periodontal Disease. A Clinical Study (PhD , Secondary Advisor)
- C. Fleckeri Mode of Action Investigation (PhD , Secondary Advisor)
- Completed
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- Articaine in dentistry: Safety, efficacy, practitioner perception and evidence-based practice (2023, Masters , Secondary Advisor)
- The effect of substance P (SP) on adhesion of Jurkat leukemia cells and squamous carcinoma cells (SCC) to vascular endothelial cells and role in metastasis (2019, PhD , Primary Advisor)
- Collaboration
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The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.- 5+ collaborations
- 4 collaborations
- 3 collaborations
- 2 collaborations
- 1 collaboration
- Indicates the Tropics (Torrid Zone)
Connect with me
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My research areas
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