About

I graduated in Medicine at University of Melbourne then did a University of Melbourne MD; ‘Polymorphic Plasmodium falciparum merozoite surface antigens: temporal patterns of infection, complex genotype analysis and intragenic recombination.’ This was supervised by two outstanding malaria researchers in Ross Coppel and Alan Saul.

In my roles as Director of Clinical Research at Townsville Hospital and Professor of Medicine at JCU, I will be a focal point for developing interactions between laboratory based and clinician researchers. This will build up clinical research leading to substantial opportunities for collaborations in discovery medicine.

My own research involves clinical and laboratory investigations on the role of aspirin in prevention of sepsis as well as interrogating possible treatment for vascular disease by manipulating the lectin complement pathway.

I am working to build a large relational patient outcomes data base using the information contained in Queensland Health data sets. This project is a priority objective of the Tropical Australian Academic Health Centre. We are working towards including the five Hospital and Health Services of Northern Australia in this project.

Teaching
  • MD5010: Integrated Clinical Practice Part 1 of 3 (Level 5; TSV)
  • MD5020: Integrated Clinical Practice Part 2 of 3 (Level 5; TSV)
  • MD5030: Integrated Clinical Practice Part 3 of 3 (Level 5; TSV)
  • MD6010: Advanced Clinical Medicine Part 1 of 3 (Level 6; TSV)
  • MD6020: Advanced Clinical Medicine Part 2 of 3 (Level 6; TSV)
  • MD6030: Advanced Clinical Medicine Part 3 of 3 (Level 6; TSV)
Interests
Research
  • Aspirin’s influence on infectious diseases: Sepsis - treatment and prevention; The ANTISEPSIS study - AspiriN To Inhibit SEPSIS. ASPREE substudy, Department of Epidemiology and Preventive Medicine, Monash University. National Institutes of Ageing funded primary infection study of low dose aspirin in elderly patients. (19,000 randomised patients) CIA NH&MRC Project Grant awarded for 2013-2018 APP1041986 $391,879.56
  • Effects of aspirin on biofilm formation
  • Mannose-binding lectin (MBL) biology and its contribution inflammatory condition pathogenesis.
  • Blocking MBL in ischaemia reperfusion injury models with the aim of restricting myocardial and brain tissue loss
  • Linkage of patient information to develop and relational patient outcome database [Queensland Disease and Treatment Assessment, QLData]
Experience
  • 2017 to 2022 - Adjunct Professor of Medicine, Department of Epidemiology and Preventive Medicine,, Monash University (Melbourne)
  • 2004 to 2015 - Associate Professor, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne
  • 2003 to 2015 - Staff Infectious Diseases Physician, Victorian Infectious Diseases Service,, Royal Melbourne Hospita
  • 2003 - Associate Professor, Faculty of Medicine,, University of Queensland
  • 1996 to 2003 - Visiting Scientist., Queensland Institute of Medical Research (Brisbane)
  • 1996 to 2003 - Infectious Diseases Physician., Royal Brisbane Hospital
  • 1994 to 1995 - NH&MRC Medical Postgraduate Scholar,, Monash University (Melbourne)
Research Disciplines
Socio-Economic Objectives
Honours
Awards
  • 2002 - Australasian Society of Infectious Diseases / Amgen Australia Medical Mycology Research – Travel Grant
  • 1994 - •Royal Australasian College of Physicians Advanced Trainees Scientific Award
Fellowships
  • 2013 - •Visiting Professor, Cytokines and Inflammation Unit Division of Infection and Epidemiology, Institut Pasteur, Paris
  • 2002 - Visiting Professor, Montefiore Medical Centre, New York City
Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles
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ResearchOnline@JCU stores 61+ research outputs authored by Prof Damon Eisen from 2007 onwards.

Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

Tropical Australian Academic Health Centre Limited - Research Seed Grants

Revealing the hidden knowledge in pathology big data: Machine learning to support clinical decision making for unknown infectious diseases and recognise biosecurity incursions in tropical Australia

Indicative Funding
$48,480 over 3 years
Summary
Pathology departments generate massive data from the results of routine and targeted tests conducted to serve community health needs. With the availability of large pathology data collections, the application of sophisticated machine learning (ML) algorithms allows the detection of novel data patterns to characterise disease processes and monitor population health. We will apply recursive partitioning (trees and forests) and support vector machines (SVM) to large pathology data sets to: (a) investigate the biosecurity potential of linked community data, and; (b) assist early decision support for patients presenting with a tropical pyrexia of unknown origin (PUOs).
Investigators
Jeffrey Warner and Damon Eisen in collaboration with Emma McBryde, Catherine Rush and Brett Lidbury (College of Public Health, Medical & Vet Sciences, Australian Institute of Tropical Health & Medicine and Australian National University)
Keywords
Big data; Pathology; Biosecurity; Meloidosis; Arboviral disease; Machine learning

Tropical Australian Academic Health Centre Limited - Contract Research

Can portable genome sequencing provide a rapid, comprehensive, point-of-care diagnostic test for Far North Queensland hospitals and healthcare centres?

Indicative Funding
$49,987 over 2 years
Summary
Respiratory disease, fevers, and sepsis are common in FNQ and treatment often requires admission to hospital. These infections have many different causes, and diagnosing them requires multiple tests that take weeks to perform. Consequently, patients are treated with broad-spectrum antibiotics before a pathogen is identified, leading to poorer outcomes for the patient and contributing to the spread of antibiotic-resistant infections. We will trial new genome sequencing technology as a point-of-care diagnostic test for fever, sepsis, and pneumonia at Cairns Hospital, and test the hypothesis that this approach will increase the proportion of infections that are diagnosed and reduce the time-to-diagnosis.
Investigators
John McBride, Cadhla Firth, Simon Smith, Joshua Hanson, Matt Field, Emma McBryde, John Miles, Damon Eisen and Christopher Heather (College of Medicine & Dentistry, Australian Institute of Tropical Health & Medicine and Queensland Health)
Keywords
Genomics; Healthcare; pathogens

Queensland Health - Queensland Genomics Health Alliance Project Fund

Pathogen Genomics North Queensland

Indicative Funding
$180,000 over 1 year (administered by The University of Queensland)
Summary
This project will develop pathogen genomics to improve time to best treatment of serious infectious diseases. We aim to incorporate pathogen genomics into the workflow of clinical microbiology units in regional Queensland Health Hospitals for investigation of potential or known infectious disease.
Investigators
Emma McBryde and Damon Eisen in collaboration with John McBride, Matt Field, Luke Lawton, Geoff Gordon and Richard Stone (Australian Institute of Tropical Health & Medicine, College of Medicine & Dentistry and Townsville Hospital and Health Service)
Keywords
Genomics; Sequencing; Infectious Disease; Microbiology
Supervision

Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current
  • Psychological intervention for reducing emergency department (ED) representations ?? A randomised controlled trial (RCT) (PhD , Secondary Advisor)
  • Environmental and socio-demographic predictors of Bacteraemia in North Queensland (PhD , Secondary Advisor)
Completed
  • Development of adjuvant therapy to treat biofilm-related Staphylococcus aureus prosthetic joint infection (2022, PhD , Primary Advisor)
Collaboration

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.

  • 5+ collaborations
  • 4 collaborations
  • 3 collaborations
  • 2 collaborations
  • 1 collaboration
  • Indicates the Tropics (Torrid Zone)

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