Dr Daniel Xing ~ JCU Senior Lecturer

Dr Daniel Xing is a radiation oncologist specializing in managing head and neck cancer, cutaneous (skin) cancer, lung cancer and brain tumors. Having completed his specialist training in Peter MacCallum Cancer Centre in 2020 and head and neck cancer fellowship training in Olivia Newton-John Cancer Wellness & Research Centre at Austin Health in 2021, he commenced a position as staff specialist at the Department of Radiation Oncology at Townsville Cancer Centre, Townville University Hospital in 2022. He is the chair of the head and neck cancer multidisciplinary clinic, the only comprehensive head and neck cancer service serving a population of more than 250,000 people located across 150,000km2 of northern Queensland.

In addition to maintaining a busy public practice, Dr Xing has the passion of both clinical and translational research. Prior to his radiation oncology training, he has gained extensive lab-based research experience at Macquarie University (Sydney) and the Florey Institute of Neuroscience, University of Melbourne. He was awarded multiple prizes from the American Physiological Society for his study on the autonomic nervous system plasticity in obstructive sleep apnoea, heart failure and hypertension. His research areas are multidisciplinary ranging from development of precision oncology medicine using imaging and serum biomarkers to interaction of radiotherapy and immune therapy in cancer treatment to health economics in radiotherapy service delivery. He has established collaborations with the Australian Institute of Tropical Health & Medicine, University of Sunshine Coast, Olivia Newton-John Cancer Wellness & Research Centre, Health Economics Department at Deakin University.

Dr Xing has been funded by the Tropical Australian Academic Health Centre (TAACH), The Royal Australian and New Zealand College of Radiologists (RANZCR), and Avant Mutual Group Limited (AVANT).

Current/recent research projects:

• Implementation of intracranial stereotactic radiosurgery (SRS) service for brain metastasis in North Queensland, TAACH project grant.
• Merkel cell carcinoma: Real-world experience from a high-UV population with an emphasis on the role of polyomavirus, University of Sunshine Coast project grant.
• Stereotactic ablative radiotherapy and T cell biodistribution for oligoprogressive head and neck cancer (START-HN), RANZCR project grant.
• Systemic use of circulating biomarkers to predict treatment response in patients with oropharyngeal cancer, AVANT project grant.

Dr Xing is passionate to improve the radiotherapy service for patients from regional, rural and remote northern Queensland and First Nation patients via state-of-art radiotherapy technology, clinical and translational research, and health economics research.

Interests

Research

• Precision oncology medicine using imaging and serum biomarkers to improve screening, diagnosis, risk stratification and personalized medicine
• Health economics in oncology service delivery

Experience

• 2022 to present - Radiation Oncologist, Townsville University Hospital (Townsville)
• 2022 to present - Senior Lecturer, James Cook University (Townsville)
• 2021 to 2022 - Clinical Research Fellow, Oliver Newton-John Cancer Wellness & Research Centre, Austin Health (Melbourne)
• 2017 to 2021 - Radiation Oncology Advanced Trainee, Peter MacCallum Cancer Centre (Melbourne)
• 2012 to 2013 - Post-doctoral Research Fellow, The Florey Institute of Neuroscience and Mental Health, University of Melbourne (Melbourne)

Research Disciplines

• Oncology and carcinogenesis (3211)
• Neurosciences (3209)
• Health services and systems (4203)

Socio-Economic Objectives

• Clinical health (2001)

Awards

• 2020 - Attendance Grant, Trans-Tasman Radiation Oncology Group Annual Scientific Meeting, Sydney, Australia
• 2018 - Varian Medical Systems Educational Travel Grant, The Royal Australian and New Zealand College of Radiologists, Annual Scientific Meeting, Canberra, Australia
• 2014 - International Early Career Physiologist Travel Award, the American Physiological Society, Experimental Biology, San Diego CA, USA
• 2014 - Caroline tum Suden/Francis A. Hellebrandt Professional Opportunity Awards, the American Physiological Society, Experimental Biology, San Diego CA, USA
• 2011 - International Early Career Physiologist Travel Award, the American Physiological Society, Experimental Biology, Washington DC, USA
• 2010 - Best Poster Award of Central Cardiovascular Control: Future Directions, Sydney, Australia
• 2002 - Golden Prize of the Medical Education Scholarship of the United Laboratories, United Laboratories, Inc.
• 2019 to 2020 - Education Grant, Peter MacCallum Cancer Centre, Melbourne, Australia
• 2010 to 2011 - Student Travel Award, HBPRCA's 32nd and 33rd Annual Scientific Meeting, Melbourne, Australia
• 2001 to 2004 - Scholarship of Shanghai Jiaotong University School of Medicine

Fellowships

• 2022 - The Royal Australian and New Zealand College of Radiologists

Memberships

• 2022 - Economics and Workforce Committee, Faculty of Radiation Oncology, The Royal Australian and New Zealand College of Radiologist
• 2022 - Australian and New Zealand Head & Neck Cancer Society
• 2022 - Clinical Trials Management Working Group, Townsville Hospital and Health Service
• 2021 - TROG Cancer Research; TROG Head, Neck and Skin Working Party
• 2021 - Cooperative Trials group for Neuro-Oncology
• 2013 - Australian Medical Association

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU.

Journal Articles

• Ermongkonchai T, Khor R, Wada M, Lau E, Xing D and Ng S (2023) A review of diffusion-weighted magnetic resonance imaging in head and neck cancer patients for treatment evaluation and prediction of radiation-induced xerostomia. Radiation Oncology, 18 (1).
• Fotinopoulos P, Corry J, Ping Ng S, Dunning J, Lyons B and Xing D (2023) Nasal packing does not affect the dosimetry of sinonasal cancers treated with intensity-modulated radiotherapy or volumetric-modulated arc therapy. International Journal of Radiology & Radiation Therapy, 10 (2). pp. 32-38
• Marwah R, Xing D, Squire T, Soon Y, Gan H and Ng S (2023) Reirradiation versus systemic therapy versus combination therapy for recurrent high-grade glioma: a systematic review and meta-analysis of survival and toxicity. Journal of Neuro-Oncology, 164 (3). pp. 505-524
• Xing D, Yilmaz H, Hettige S, Hegde R and Nair R (2021) Successful Treatment of Malignant Priapism by Radiotherapy: Report of a Case, Review of the Literature, and Treatment Recommendations. Cureus, 13 (8).
• Xing D, Khor R, Gan H, Wada M, Ermongkonchai T and Ng S (2021) Recent research on combination of radiotherapy with targeted therapy or immunotherapy in head and neck squamous cell carcinoma: A review for radiation oncologists. Cancers, 13 (22).
• Xing D, Tiong A, Bressel M, Rischin D, Tran P and Corry J (2020) Outcomes of curative (chemo)radiotherapy for patients with non-p16 positive head and neck squamous cell carcinoma who are borderline for curative treatment. Journal of Medical Imaging and Radiation Oncology, 64 (2). pp. 271-278
• Ramchandra R, Xing D, Matear M, Lambert G, Allen A and May C (2019) Neurohumoral interactions contributing to renal vasoconstriction and decreased renal blood flow in heart failure. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 317 (3). pp. R386-R396
• Xing D, Siva S and Hanna G (2019) The abscopal effect of stereotactic radiotherapy and immunotherapy – fool’s gold or el dorado? Clinical Oncology, 31 (7). pp. 432-443
• Ramchandra R, Hood S, Xing D, Lambert G and May C (2018) Mechanisms underlying the increased cardiac norepinephrine spillover in heart failure. American Journal of Physiology-Heart and Circulatory Physiology, 315 (2). pp. H340-H347
• Wang F, Yin J, Lu Z, Zhang G, Li J, Xing T, Zhuang S and Wang N (2016) Limb ischemic preconditioning protects against contrast-induced nephropathy via renalase. EBioMedicine, 9. pp. 356-365

Other research outputs

• Sabesan S, Xing D and Gallo J (2022) Telemedicine platforms must be leveraged to strengthen rural health systems. Journal of Medical Radiation Sciences, 69 (3). pp. 277-278
• Xing D, Hettige S, Yan Shan Chee L, Nair R and Hegde R (2021) Curative Radiotherapy for Locally Advanced Scalp Squamous Cell Carcinoma. Cureus, 13 (10).