Professor Schofield is inaugural Director of the Australian Institute of Tropical Health and Medicine (AITHM). He was for 24 years an NHMRC Research Fellow at the Walter and Eliza Hall Institute in Melbourne, has twice held an International Research Scholarship of the Howard Hughes Medical Institute, and was co-founder of Ancora Pharmaceuticals Inc. A recognised authority in the immunology and pathogenesis of infectious diseases, his research programs cover basic molecular sciences, product development and commercialisation, epidemiology and public health. His approach to malaria has resulted in promising vaccine development programs, and clinical trials in Papua New Guinea and Africa. He has published key articles in the highest ranked international journals and received over 6,500 citations.

Research Disciplines

• Immunology (1107)
• Medical Microbiology (1108)

Socio-Economic Objectives

• Clinical Health (9201)

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles

• Joseph H, Tan Q, Mazhari R, Eriksson E and Schofield L (2019) Vaccine-induced carbohydrate-specific memory B cells reactivate during rodent malaria infection. Frontiers in Immunology, 10, Article: 1840, DOI:10.3389/fimmu.2019.01840.
• Pawliw R, Farrow R, Sekuloski S, Jennings H, Healer J, Phuong T, Sathe P, Pasay C, Evans K, Cowman A, Schofield L, Chen N, McCarthy J and Trenholme K (2018) A bioreactor system for the manufacture of a genetically modified Plasmodium falciparum blood stage malaria cell bank for use in a clinical trial. Malaria Journal, 17, Article: 283, DOI:10.1186/s12936-018-2435-x.
• Sampaio N, Kocan M, Schofield L, Pfleger K and Eriksson E (2018) Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression. PLoS ONE, 13 (8), Article: e0202408, DOI:10.1371/journal.pone.0202408.
• Sampaio N, Emery S, Garnham A, Tan Q, Sisquella X, Pimentel M, Jex A, Regev-Rudzki N, Schofield L and Eriksson E (2018) Extracellular vesicles from early stage Plasmodium falciparum‐infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes. Cellular Microbiology, 20 (5), Article: e12822, DOI:10.1111/cmi.12822.
• Sampaio N, Eriksson E and Schofield L (2018) Plasmodium falciparum PfEMP1 modulates monocyte/macrophage transcription factor activation and cytokine and chemokine responses. Infection and Immunity, 86 (1), Article: e00447-17, DOI:10.1128/IAI.00447-17.
• Franca C, Li Wai Suen C, Carmagnac A, Lin E, Kiniboro B, Siba P, Schofield L and Mueller I (2017) IgG antibodies to synthetic GPI are biomarkers of immune-status to both Plasmodium falciparum and Plasmodium vivax malaria in young children. Malaria Journal, 16, Article: 386, DOI:10.1186/s12936-017-2042-2.
• Hill D, Schofield L and Wilson D (2017) IgG opsonization of merozoites: multiple immune mechanisms for malaria vaccine development. International Journal for Parasitology, 47 (10-11), pp. 585-595, DOI:10.1016/j.ijpara.2017.05.004.
• Moraleda C, Aguilar R, Quinto L, Nhampossa T, Renom M, Nhabomba A, Acacio S, Aponte J, Nhalungo D, Achtman A, Schofield L, Martins H, Macete E, Alonso P and Menendez C (2017) Anaemia in hospitalised preschool children from a rural area in Mozambique: a case control study in search for aetiological agents. BMC Pediatrics, 17 (63), DOI:10.1186/s12887-017-0816-x.
• Schofield L, Ioannidis L, Karl S, Robinson L, Tan Q, Poole D, Betuela I, Hill D, Siba P, Hansen D, Mueller I and Eriksson E (2017) Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of gamma delta T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea. BMC Medicine, 15, Article: 114, DOI:10.1186/s12916-017-0883-8.
• Sisquella X, Ofir-Birin Y, Pimentel M, Cheng L, Abou Karam P, Sampaio N, Penington J, Connolly D, Giladi T, Scicluna B, Sharples R, Waltmann A, Avni D, Schwartz E, Schofield L, Porat Z, Hansen D, Papenfuss A, Eriksson E, Gerlic M, Hill A, Bowie A and Regev-Rudzki N (2017) Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors. Nature Communications, 8, Article: 1985, DOI:10.1038/s41467-017-02083-1.
• Srivastava A, Evans K, Sexton A, Schofield L and Creek D (2017) Metabolomics-based elucidation of active metabolic pathways in erythrocytes and HSC-derived reticulocytes. Journal of Proteome Research, 16 (4), pp. 1492-1505, DOI:10.1021/acs.jproteome.6b00902.
• Hill D, Wilson D, Sampaio N, Eriksson E, Ryg-Cornejo V, Harrison G, Uboldi A, Robinson L, Beeson J, Siba P, Cowman A, Hansen D, Mueller I and Schofield L (2016) Merozoite antigens of Plasmodium falciparum elicit strain-transcending psonizing immunity. Infection and Immunity, 84 (8), pp. 2175-2184, DOI:10.1128/IAI.00145-16.

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ResearchOnline@JCU stores 45+ research outputs authored by Prof Louis Schofield from 2008 onwards.

Current and recent Research Funding to JCU is shown by funding source and project.

Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current

• Defining transmission of malaria parasites from humans to mosquitos in Papua New Guinea (PhD , Secondary Advisor/AM)

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.