JCU > Research Portfolio > Dr Erik Biros

About

Research Disciplines: Cardiovascular medicine and haematology (3201)

Clinical sciences (3202)
Socio-Economic Objectives: Clinical health (2001)

Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles

Dobson G, Biros E, Letson H and Morris J (2021) Living in a hostile world: inflammation, new drug development, and coronavirus. Frontiers in Immunology, 11, Article: 610131, DOI:10.3389/fimmu.2020.610131.
Krishna S, Li J, Wang Y, Moran C, Trollope A, Mohamed Omer S, Huynh P, Jose R, Biros E, Ma J and Golledge J (2021) Kallistatin limits abdominal aortic aneurysm by attenuating generation of reactive oxygen species and apoptosis. Scientific Reports, 11, Article: 17451, DOI:10.1038/s41598-021-97042-8.
Moran C, Biros E, Krishna S, Morton S, Sexton D and Golledge J (2021) Kallikrein-1 blockade inhibits aortic expansion in a mouse model and reduces prostaglandin E2 secretion from human aortic aneurysm explants. Journal of the American Heart Association, 10 (5), DOI:10.1161/JAHA.120.019372.
Morris J, Letson H, McEwen P, Biros E, Dlaska C, Hazratwala K, Wilkinson M and Dobson G (2021) Intra-articular Adenosine, Lidocaine and Magnesium (ALM) solution decreases postoperative joint fibrosis in an experimental knee implant model. Translational Medicine Communications, 6, Article: 4, DOI:10.1186/s41231-021-00084-3.
AL-ABBAD H, ALLEN S, Morris S, Reznik J, Biros E, PAULIK B, Wright A and (2020) The effects of shockwave therapy on musculoskeletal conditions based on changes in imaging: a systematic review and meta-analysis with meta-regression. BMC Musculoskeletal Disorders, 21, Article: 275, DOI:10.1186/s12891-020-03270-w.
Biros E and Moran C (2020) Mini tryptophanyl-tRNA synthetase is required for a synthetic phenotype in vascular smooth muscle cells induced by IFN-gamma-mediated beta 2-adrenoceptor signaling. Cytokine, 127, Article: 154940, DOI:10.1016/j.cyto.2019.154940.
Moran C, Seto S, Biros E, Krishna S, Morton S, Kleinschnitz C, Panousis C and Golledge J (2020) Factor XII blockade inhibits aortic dilatation in angiotensin II-infused apolipoprotein E-deficient mice. Clinical Science, 134 (9), pp. 1049-1061, DOI:10.1042/CS20191020.
Sheridan M, Koeberl M, Hedges C, Biros E, Ruethers T, Clarke D, Buddhadasa S, Kamath S and Lopata A (2020) Undeclared allergens in imported packaged food for retail in Australia. Food Additives & Contaminants: Part A, 37 (2), pp. 183-192, DOI:10.1080/19440049.2019.1679890.
Langdon K, Phie J, Thapa C, Biros E, Loukas A and Haleagrahara N (2019) Helminth-based therapies for rheumatoid arthritis: a systematic review and meta-analysis. International Immunopharmacology, 66, pp. 366-372, DOI:10.1016/j.intimp.2018.11.034.
Letson H, Morris J, Biros E and Dobson G (2019) Conventional and specific-pathogen free rats respond differently to anesthesia and surgical trauma. Scientific Reports, 9, Article: 9399, DOI:10.1038/s41598-019-45871-z.
Letson H, Morris J, Biros E and Dobson G (2019) ALM fluid therapy leads to 72 hr survival after hemorrhagic shock. Journal of Trauma and Acute Care Surgery, 87 (3), pp. 606-613, DOI:10.1097/TA.0000000000002397.
Dewdney B, Trollope A, Moxon J, Thomas Manapurathe D, Biros E and Golledge J (2018) Circulating microRNAs as biomarkers for acute ischemic stroke: a systematic review Journal of Stroke and Cerebrovascular Diseases. Journal of stroke and cerebrovascular diseases, 27 (3), pp. 522-530, DOI:10.1016/j.jstrokecerebrovasdis.2017.09.058.

More: ResearchOnline@JCU stores 64+ research outputs authored by Dr Erik Biros from 2005 onwards.

Current Funding

Current and recent Research Funding to JCU is shown by funding source and project.

United States Department of Defence - DoD Peer Reviewed Orthopaedic Research Program (PRORP) - Applied Research Award

ALM Drug Therapy to reduce inflammation and scar formation after ACL reconstruction surgery: Targeting earlier return to active duty.

Indicative Funding: $1,061,864 over 3 years
Summary: Two complications of anterior cruciate ligament (ACL) reconstruction surgery are cartilage degeneration and scarring within the joint, which can prolong healing, promote pain and restrict knee movement. Our project will evaluate a new therapy known as ALM solution that can be administrered during ACL reconstruction surgery to dampen inflammation, protect cartilage and promote tissue healing within the joint. Our study has the potential to expedite a patient's return to an active duty with fewer complications.
Investigators: Geoffrey Dobson, Peter McEwen, Jodie Morris, Hayley Letson and Erik Biros (College of Medicine & Dentistry)
Keywords: ACL Injury; ACL Reconstruction surgery; Scarring; Osteoarthritis; Inflammation; Therapeutics

Department of Health and Ageing - Pharmacy Trial Program

Integrated Practice Pharmacists within Aboriginal Community Controlled Health Services

Indicative Funding: $1,040,046 over 2 years (administered by Pharmaceutical Society of Australia)
Summary: Aboriginal and Torres Strait Islander peoples experience a much higher burden of disease due to heart disease, diabetes and other chronic health problems. Many deaths from these illnesses can be prevented if patients are better supported to take their medicines and prescribing quality is improved. This trial will explore if including a practice pharmacist in the primary health care team within Aboriginal community controlled health services (ACCHSs) leads to improvements in the quality of care that Aboriginal and Torres Strait Islander people receive. Our trial will tell us if prescribing by doctors is improved, if patients are more likely to take their medicines, and if indicators of their health are improving over time.
Investigators: Sophie Couzos, Rhondda Jones, Emily Callander, Erik Biros, Deb Smith, Michelle Bellingan, Beverley Glass, Priscilla Page, Donald Whaleboat, Robyn Preston, Nicole Bates, Douglas Boyle, Vicki Slinko, Roderick Wright, Nadia Lusis, Elizabeth Moore and Kathryn Panaretto (College of Medicine & Dentistry, Division of Tropical Health & Medicine, College of Public Health, Medical & Vet Sciences, The University of Melbourne, Queensland Aboriginal and Islander Health Council, Victorian Aboriginal Community Controlled Health Organisation, Aboriginal Medical Services Alliance Northern Territory and Gidgee Healing Mount Isa Aboriginal Community Controlled Health Services Ltd)
Keywords: Aboriginal Health; integrated health care; continuing quality improvement; Primary Health Care; practice pharmacist; community based participatory research

Supervision

Advisory Accreditation: I can be on your Advisory Panel as a Primary or Secondary Advisor.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current

Hydrotherapy as a Treatment Regimen for Patients with Intensive Care Unit (ICU) Aquired Weakness (PhD , Secondary Advisor)
Physiotherapy for Patients with Persisting COVID-19 Complications: Development of a long Covid Rehabilitation Program (PhD , Secondary Advisor)

Completed

Neurogenic heterotopic ossification: prevalence, risk factors, management and treatment (2016, PhD , Associate Advisor)

Collaboration

The map shows research collaborations by institution from the past 7 years.
Note: Map points are indicative of the countries or states that institutions are associated with.