About

Dr Barratt is passionate about cell biology and elucidating the underlying mechanisms of disease.

After completing her Bachelor of Biological Science (2009, University of Western Sydney) and Honours degree (2010) in embryology at the Children’s Medical Research Institute (Westmead, UWS) Kristen relocated to Canberra to undertake her Ph.D. in the Early Mammalian Development Laboratory with Professor Ruth Arkell at the Australian National University (ANU). Durng her PhD she worked on elucidating the non-coding regulatory mechanisms behind Zic2-associated Holoprosencephaly (HPE), discovered an association between HPE and left-right axis defects/Heterotaxy and was awarded the Wood-Whelan Research Fellowship and Company of Biologists (Development) Travelling Fellowship (2013).

Post-PhD, Dr Barratt continued her research as a Postdoctoral Fellow at the John Curtin School of Medical Research (ANU) where she demonstrated that elevated canonical WNT signalling causes L-R axis defects and Heterotaxy for the first time, and also generated the first genetic mouse model of maternal type 2 diabetes and diabetic embryopathy. Her work on canonical WNT signalling earnt her The Verne Chapman Young Scientist Award (2020, Internantional Mammalian Genome Society).

In 2023 Dr Barratt moved to Townsville and began working with Professor Jon Golledge and the QRCPVD to investigate the role of canonical WNT signalling in abdominal aortic aneurysms and vascular disease.  

Concurrently, Dr Barratt participates in extensive teaching, educating students from a high school level all the way through to post-graduate students, and is an advocate for Women and Girls in STEMM fields.

Research Disciplines
Socio-Economic Objectives
Publications

These are the most recent publications associated with this author. To see a detailed profile of all publications stored at JCU, visit ResearchOnline@JCU. Hover over Altmetrics badges to see social impact.

Journal Articles
Book Chapters
  • Barratt K and Arkell R (2018) ZIC2 in Holoprosencephaly. In: Zic family: Evolution, Development and Disease. Advances in Experimental Medicine and Biology, 1046. Springer, Singapore, pp. 269-299
Supervision

Advisory Accreditation: I can be on your Advisory Panel as a Secondary Advisor.

These Higher Degree Research projects are either current or by students who have completed their studies within the past 5 years at JCU. Linked titles show theses available within ResearchOnline@JCU.

Current
  • Evaluation of the Effect of a Direct 5' Adenosine Monophosphate-activated protein (AMP) Kinase (AMPK) Activator in Inhibiting Abdominal Aortic Aneurysms (AAA) in Mouse Model (PhD , Secondary Advisor)
  • Investigating a novel potential therapy for abdominal aortic aneurysm (PhD , External Advisor)
  • Effect of interleukin-6 blocking antibody on aneurysm growth in an elastase-BAPN induced abdominal aortic aneurysm mouse model (PhD , Secondary Advisor)
  • Using rodent models to develop new treatments for aortic aneurysm (PhD , Secondary Advisor)

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